Results 161 to 170 of about 409,451 (306)
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells. [PDF]
, 1989 Nico J. Stam +6 more
openalex +1 more source
Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
Advanced Healthcare Materials, EarlyView.The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao +7 more
wiley +1 more source
Hyperthyroxinemic mice have reduced natural killer cell activity. Evidence for a defective trigger mechanism. [PDF]
, 1987 Joan Stein‐Streilein +3 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail +3 more
wiley +1 more source
Natural killer cells: definition of a cell type rather than a function. [PDF]
, 1986 L L Lanier +4 more
openalex +1 more source
Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury
Advanced Healthcare Materials, EarlyView.A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum +28 more
wiley +1 more source
Effect of virus infections on target cell susceptibility to natural killer cell-mediated lysis. [PDF]
, 1980 Raymond M. Welsh, Linda A. Hallenbeck
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan +13 more
wiley +1 more source