Results 101 to 110 of about 9,361,396 (309)

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

open access: yesAdvanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo   +9 more
wiley   +1 more source

Natural Killer Cells

open access: yes, 2017
The book Natural Killer Cells is the result of a collective work that addresses in a clear and comprehensive way for readers and through as many sensuous details as possible, the most and various fundamental aspects of natural killer cells, as well as ...

core   +1 more source

Natural killer cells and autoimmunity.

open access: yesArthritis research & therapy, 2004
Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppressing autoimmunity.
French, Anthony R, Yokoyama, Wayne M
openaire   +2 more sources

Turning on Natural Killer Cells [PDF]

open access: yesThe Journal of Experimental Medicine, 2000
NK cells preferentially recognize and kill cells that lack expression of MHC class I ([1][1]). While inhibitory receptors expressing immunoreceptor tyrosine-based inhibition motifs prevent NK cells from harming tissues expressing normal levels of classical or nonclassical MHC class I (for a review,
openaire   +2 more sources

Impaired cytotoxicity associated with defective natural killer cell differentiation in myelodysplastic syndromes

open access: yesHaematologica, 2015
Natural killer cells are well known to mediate anti-leukemic responses in myeloid leukemia but their role in myelodysplastic syndromes is not well understood.
Maryam Hejazi   +9 more
doaj   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

open access: yesAdvanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Cytokine-induced killer cells are type II natural killer T cells

open access: yesGMS German Medical Science, 2007
Background: Until now, cytokine-induced killer (CIK) cells were assumed to be part of the type I natural killer T (NKT) cell population, but it was not yet investigated if this is correct.
Schmidt-Wolf, Ingo G.H.   +3 more
doaj  

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

open access: yesAdvanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye   +11 more
wiley   +1 more source

Biology of Natural Killer Cells

open access: yes, 1989
Studies of cytotoxicity by human lymphocytes revealed not only that both allogeneic and syngeneic tumor cells were lysed in a non-MHC-restricted fashion, but also that lymphocytes from normal donors were often cytotoxic. Lymphocytes from any healthy donor, as well as peripheral blood and spleen lymphocytes from several experimental animals, in the ...
openaire   +2 more sources

Interferon therapy shifts natural killer subsets among egyptian patients with chronic hepatitis C

open access: yesBrazilian Journal of Infectious Diseases
Natural killer cells can be divided into five subpopulations based on the relative expression of CD16 and CD56 markers. The majority of natural killer cells are CD56dim, which are considered to be the main cytotoxic effectors.
Amal Fathy   +5 more
doaj   +1 more source

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