Results 81 to 90 of about 401,106 (204)
The role of natural killer cells in chronic myeloid leukemia
Revista Brasileira de Hematologia e Hemoterapia, 2011 Chronic myeloid leukemia is a neoplasia resulting from a translocation between chromosomes 9 and 22 producing the BCR-ABL hybrid known as the Philadelphia chromosome (Ph).
Anna Carolyna Araújo Danier +3 more
doaj +1 more source
RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. [PDF]
, 2012 The NKG2D stimulatory receptor expressed by natural killer cells and T cell subsets recognizes cell surface ligands that are induced on transformed and infected cells and facilitate immune rejection of tumor cells.
Hsiung, Benjamin +4 more
core +2 more sources
Haematologica, 2015 Natural killer cells are well known to mediate anti-leukemic responses in myeloid leukemia but their role in myelodysplastic syndromes is not well understood.
Maryam Hejazi +9 more
doaj +1 more source
Natural killer cell response to chemotherapy-stressed cancer cells: Role in tumor immunosurveillance. [PDF]
, 2017 Natural killer (NK) cells are innate cytotoxic lymphoid cells that actively prevent neoplastic development, growth, and metastatic dissemination in a process called cancer immunosurveillance.
Borrelli, Cristiana +5 more
core +1 more source
BMJ Case Reports, 2009 A 42-year-old white woman, who was a general practitioner referral to the medical team, presented with a 3-day history of left upper quadrant pain; an urgent private ultrasound scan had showed splenomegaly. She was initially admitted with sepsis without an obvious cause but with a differential diagnosis of a haematological malignancy.
openaire +3 more sources
Haematologica, 2014 Natural killer cells are the first lymphocyte subset to reconstitute, and play a major role in early immunity after allogeneic hematopoietic stem cell transplantation.
Vissal David Kheav +17 more
doaj +1 more source
Environmental stimuli shape microglial plasticity in glioma [PDF]
, 2017 In glioma, microglia and infiltrating macrophages are exposed to factors that force them to produce cytokines and chemokines, contributing to tumor growth and maintaining a pro-tumorigenic, immunosuppressed microenvironment.
Alboni +59 more
core +2 more sources
Cytokine-induced killer cells are type II natural killer T cells
GMS German Medical Science, 2007 Background: Until now, cytokine-induced killer (CIK) cells were assumed to be part of the type I natural killer T (NKT) cell population, but it was not yet investigated if this is correct.
Schmidt-Wolf, Ingo G.H. +3 more
doaj
Interferon therapy shifts natural killer subsets among egyptian patients with chronic hepatitis C
Brazilian Journal of Infectious DiseasesNatural killer cells can be divided into five subpopulations based on the relative expression of CD16 and CD56 markers. The majority of natural killer cells are CD56dim, which are considered to be the main cytotoxic effectors.
Amal Fathy +5 more
doaj +1 more source
Killers at the crossroads: The use of innate immune cells in adoptive cellular therapy of cancer
Stem Cells Translational Medicine, 2020 Adoptive cell therapy (ACT) is an approach to cancer treatment that involves the use of antitumor immune cells to target residual disease in patients after completion of chemo/radiotherapy.
May Sabry, Mark W. Lowdell
doaj +1 more source