Results 211 to 220 of about 388,404 (259)
Some of the next articles are maybe not open access.
Natural killer cell metabolism
Molecular Immunology, 2019Natural killer (NK) cells are a critical component in the innate immune response against disease. NK cell function is tightly regulated by specific cytokine and activation/inhibitory receptor signalling, leading to diverse effector responses. Like all living cells, energy metabolism is a fundamental requirement for NK cell activation and survival ...
Kobayashi, Takumi +1 more
openaire +3 more sources
Nature Immunology, 2011
Natural killer (NK) cells are bone marrow–derived granular lymphocytes that have a key role in immune defense against viral and bacterial infections and malignancies. NK cells are traditionally defined as cells of the innate immune response because they lack RAG recombinase–dependent clonal antigen receptors.
Silke, Paust, Ulrich H, von Andrian
openaire +2 more sources
Natural killer (NK) cells are bone marrow–derived granular lymphocytes that have a key role in immune defense against viral and bacterial infections and malignancies. NK cells are traditionally defined as cells of the innate immune response because they lack RAG recombinase–dependent clonal antigen receptors.
Silke, Paust, Ulrich H, von Andrian
openaire +2 more sources
CRC Critical Reviews in Clinical Laboratory Sciences, 1985
It is proposed that this article will encompass a review of primarily the human natural killer cell. The following parameters of the human natural killer (NK) cell will be reviewed: its ontogeny; surface membrane characteristics including monoclonal antibody reactivity, cell lineage, the natural killer sensitive targets, and the proposed mechanism of ...
openaire +2 more sources
It is proposed that this article will encompass a review of primarily the human natural killer cell. The following parameters of the human natural killer (NK) cell will be reviewed: its ontogeny; surface membrane characteristics including monoclonal antibody reactivity, cell lineage, the natural killer sensitive targets, and the proposed mechanism of ...
openaire +2 more sources
Veterinary Immunology and Immunopathology, 2009
Natural killer (NK) cells have received much attention due to their cytotoxic abilities, often with a focus on their implications for cancer and transplantation. But despite their name, NK cells are also potent producers of cytokines like interferon-gamma.
Preben, Boysen, Anne K, Storset
openaire +2 more sources
Natural killer (NK) cells have received much attention due to their cytotoxic abilities, often with a focus on their implications for cancer and transplantation. But despite their name, NK cells are also potent producers of cytokines like interferon-gamma.
Preben, Boysen, Anne K, Storset
openaire +2 more sources
Hospital Practice, 1982
Named for their apparent ability to function without prior sensitization, NK cells are the newest additions to the growing cast of immunopathologic effectors, which includes antibodies and immune complexes as well as cytolytic T cells and K cells. The understanding of NK activity has progressed to a level that permits investigators to consider its ...
openaire +4 more sources
Named for their apparent ability to function without prior sensitization, NK cells are the newest additions to the growing cast of immunopathologic effectors, which includes antibodies and immune complexes as well as cytolytic T cells and K cells. The understanding of NK activity has progressed to a level that permits investigators to consider its ...
openaire +4 more sources
Natural killer cells and natural killer T cells
Arthritis & Rheumatism, 2000NK cells are important in protecting against viral infections, and they may regulate the immune response. They are activated by hematopoietic blasts and pose a barrier to bone marrow transplantation. They are also abundant in the pregnant uterine decidua, although their role there is unknown.
openaire +2 more sources
Current Hematologic Malignancy Reports, 2009
The natural killer (NK)-cell neoplasms are rare, representing less than 1% of non-Hodgkin lymphoma, except in Asia and Latin America, where they represent 3% to 6%. NK-cell neoplasms include immature acute leukemias; a blastic NK-cell lymphoma, which is obsolete because of its plasmacytoid dendritic-cell origin; and mature NK neoplasms, comprising ...
John P, Greer, Claudio A, Mosse
openaire +2 more sources
The natural killer (NK)-cell neoplasms are rare, representing less than 1% of non-Hodgkin lymphoma, except in Asia and Latin America, where they represent 3% to 6%. NK-cell neoplasms include immature acute leukemias; a blastic NK-cell lymphoma, which is obsolete because of its plasmacytoid dendritic-cell origin; and mature NK neoplasms, comprising ...
John P, Greer, Claudio A, Mosse
openaire +2 more sources
Current Opinion in Immunology, 1995
In killing of cellular targets, natural killer cells employ receptors that activate them and receptors specific for MHC class I that inhibit their activation. Progress in understanding the inhibitory receptors has been rapid, and indications are that they fall into two distinct structural types that appear to utilize the same inhibitory signaling ...
openaire +3 more sources
In killing of cellular targets, natural killer cells employ receptors that activate them and receptors specific for MHC class I that inhibit their activation. Progress in understanding the inhibitory receptors has been rapid, and indications are that they fall into two distinct structural types that appear to utilize the same inhibitory signaling ...
openaire +3 more sources
Current Opinion in Immunology, 1997
The specificity in the recognition of hematopoietic target cells by natural killer cells is primarily provided by inhibitory receptors and several such receptors have been identified in the past year. Surprisingly, the recognition of MHC class I molecules by inhibitory receptors on human natural killer cells involves two different types of receptors ...
E O, Long, N, Wagtmann
openaire +2 more sources
The specificity in the recognition of hematopoietic target cells by natural killer cells is primarily provided by inhibitory receptors and several such receptors have been identified in the past year. Surprisingly, the recognition of MHC class I molecules by inhibitory receptors on human natural killer cells involves two different types of receptors ...
E O, Long, N, Wagtmann
openaire +2 more sources
Improving natural killer cells
Cytotherapy, 2008Donor lymphocyte infusions after stem cell transplantation have taught the cancer community that human immune cells have the potential power to control growth of and even eliminate a malignant clone. Although infusion of allogeneic T lymphocytes after stem cell transplantation has become part of the treatment algorithm, either to prevent or treat ...
openaire +2 more sources