Changes in T-lymphocyte subsets and natural killer cells of patients after out-of-hospital cardiac arrest and resuscitation: a retrospective study. [PDF]
Shan Z+5 more
europepmc +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar+7 more
wiley +1 more source
Natural killer cells from endurance-trained older adults show improved functional and metabolic responses to adrenergic blockade and mTOR inhibition. [PDF]
Minuzzi LG+11 more
europepmc +1 more source
Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer+9 more
wiley +1 more source
Nucleofection-based screening of chimeric antigen receptor candidates in human natural killer cells. [PDF]
Wang CQ+6 more
europepmc +1 more source
The seal louse Echinophthirius horridus has uniquely shaped setae that may reduce drag during its host's dives. Using numerical simulations, this study demonstrates that their natural inclination promotes vortex formation, minimizing friction and energy loss. These findings provide insights into biological surface adaptations and may inspire the design
Anika Preuss+3 more
wiley +1 more source
Effects of Mesenchymal Stem Cells on Functions of Chimeric Antigen Receptor-Expressing T Lymphocytes and Natural Killer Cells. [PDF]
Volarevic V+4 more
europepmc +1 more source
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu+14 more
wiley +1 more source
In-depth bioinformatics analysis uncovers the crosstalk genes and immune interactions among diagnostic markers linked to natural killer cells in patients with cirrhosis and sepsis. [PDF]
Wang YH, Wang XX.
europepmc +1 more source