Results 1 to 10 of about 9,023 (69)
Frontiers in Immunology, 2020 Natural killer (NK) cells are innate lymphocytes that directly kill tumor and pathogen-infected cells upon activation by cytokines and NK cell receptors (NKRs) without previous sensitization.
Zixi Wang +10 more
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Reduced proportion and activity of natural killer cells in patients with Graves’ disease
European Journal of Inflammation, 2020 Natural killer cells not only play important roles in protecting against viral infection and cancer but also involved in the pathogenesis of Graves’ disease.
Qingqing Yang +6 more
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BMC Immunology, 2019 Background Natural killer cell responses to virally-infected or transformed cells depend on the integration of signals received through inhibitory and activating natural killer cell receptors.
Alexandra Tremblay-McLean +4 more
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Natural Killer T and Natural Killer Cell-Based Immunotherapy Strategies Targeting Cancer
Biomolecules, 2023 Both natural killer T (NKT) and natural killer (NK) cells are innate cytotoxic lymphoid cells that produce inflammatory cytokines and chemokines, and their role in the innate immune response to tumors and microorganisms has been investigated. Especially,
Tomonori Iyoda +4 more
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Shaping of Natural Killer Cell Antitumor Activity by Ex Vivo Cultivation
Frontiers in Immunology, 2017 Natural killer (NK) cells are a promising tool for the use in adoptive immunotherapy, since they efficiently recognize and kill tumor cells. In this context, ex vivo cultivation is an attractive option to increase NK cells in numbers and to improve their
Markus Granzin +8 more
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Reduced NK cell IFN-γ secretion and psychological stress are independently associated with herpes zoster. [PDF]
PLoS ONE, 2018 The pathogenesis of herpes zoster is closely linked to reduced varicella-zoster virus-specific cell-mediated immunity. However, little is known about the interplay between natural killer cells and psychological stress in the pathogenesis of herpes zoster.
Choon Kwan Kim +5 more
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Evasion of NK cell immune surveillance via the vimentin-mediated cytoskeleton remodeling
Frontiers in Immunology, 2022 Cancer immunotherapy uses the immune system to achieve therapeutic effects; however, its effect is still limited. Therefore, in addition to immune checkpoint-based treatment, the development of other strategies that can inhibit cancer cells from ...
Jei-Ming Peng +8 more
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Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells
Haematologica, 2016 Natural killer cells are key cells of the innate immune system. Natural killer cell receptor repertoires are diversified by a stochastic expression of killer-cell-immunoglobulin-like receptors and lectin-like receptors such as NKG2 receptors.
Loredana Ruggeri +10 more
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Current landscape of clinical use of ex vivo expanded natural killer cells for cancer therapy [PDF]
Einstein (São Paulo)Natural Killer cells are immune leukocytes required for responses against tumor cells and virus-infected cells. In the last decade, natural killer cells have emerged as promising tools in cancer therapy, and clinical studies on patients treated with ...
Júlia Teixeira Cottas de Azevedo +11 more
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Deciphering Natural Killer Cell Homeostasis
Frontiers in Immunology, 2020 Natural killer (NK) cells have a central role within the innate immune system, eliminating virally infected, foreign and transformed cells through their natural cytotoxic capacity.
Aline Pfefferle +9 more
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