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Targeting natural killer cells and natural killer T cells in cancer [PDF]
Nature Reviews Immunology, 2012 Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share some phenotypical and functional similarities. Both cell types can rapidly respond to the presence of tumour cells and participate in antitumour immune responses. This has prompted interest in the development of innovative cancer therapies that are based on
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Glycolipids for natural killer T cells
Chemical Society Reviews, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Paul B, Savage +2 more
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Natural killer and natural killer-T cells in psoriasis
Archives of Dermatological Research, 2002Psoriasis is characterized by a dermal and epidermal infiltrate comprised predominantly of CD4(+) and CD8(+) T cells, respectively. These cells behave in an antigen-dependent manner, which suggests that psoriasis may be a T-cell-mediated autoimmune disease.
Cameron, A. +3 more
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Extranodal Natural Killer T-Cell Lymphoma
New England Journal of Medicine, 2020Extranodal Natural Killer T-Cell Lymphoma A 53-year-old man presented with fever, dyspnea, and rapidly progressive skin lesions.
Kuan-Yu, Chi, Hsiu-Nien, Shen
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Natural killer T cells and haemopoiesis
British Journal of Haematology, 2006SummaryInvariant natural killer T (iNKT) cells are a small but powerful subset of regulatory T cells involved in the modulation of a variety of normal and pathological immune responses. In contrast to conventional or other types of regulatory T cells, they are activated by glycolipid and phospholipid ligands that are presented to them by the non ...
Anastasios, Karadimitris +2 more
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Cutaneous natural killer/T-cell lymphoma
Journal of the American Academy of Dermatology, 2002Lymphomas are classified as either Hodgkin's or non-Hodgkin's. The 2 subtypes of non-Hodgkin's lymphoma that can present primarily in the skin are cutaneous T-cell lymphoma and cutaneous B-cell lymphoma, both of which tend to be low-grade malignant neoplasms.
Michael A, Radonich +2 more
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Natural killer cells and natural killer T cells
Arthritis & Rheumatism, 2000NK cells are important in protecting against viral infections, and they may regulate the immune response. They are activated by hematopoietic blasts and pose a barrier to bone marrow transplantation. They are also abundant in the pregnant uterine decidua, although their role there is unknown.
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Natural killer T cells in atherosclerosis
Nature Reviews Cardiology, 2017Atherosclerosis is a chronic inflammatory disorder that develops in response to hyperlipidaemia. Cells from both the innate and adaptive immune systems contribute to the development of atherosclerotic lesions. The role of natural killer T (NKT) cells in response to microbial pathogens and inflammatory disorders such as atherosclerosis has received ...
Godfrey S, Getz, Catherine A, Reardon
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Testicular natural killer T‐cell lymphoma
International Journal of Urology, 2005Abstract Primary testicular lymphomas account for less than 5% of all testicular neoplasms. Testicular natural killer (NK)/T‐cell lymphomas are exceptional and have a very poor prognosis. We report the case of a 30‐year‐old French Caucasian man with testicular NK/T‐cell lymphoma of the following immunophenotype: CD2+, CD3ɛ+ and CD56+.
Charles, Ballereau +6 more
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Review on natural killer/T‐cell lymphoma
Hematological Oncology, 2021Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTL) is strongly associated with Epstein–Barr virus (EBV) and has a high prevalence in Asian and in Central and South America. About 85% of ENKTLs derive from NK cells and 15% from T‐cells. Various factors have been implicated in the development of ENKTL.
Xiaohua He +3 more
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