Results 141 to 150 of about 13,213,530 (364)

Coastal tourism. The economy and the environment [PDF]

The environment is a major component in the tourist production and the tourist product. This is particularly evident in the case of coastal tourism.
Furio-I-Blasco, Elies
core  

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

, 2020
Stéphanie M. Guéret, Sasikala Thavam, Rodrigo J. Carbajo, Marco Potowski, Niklas Larsson, Göran Dahl, Anita Dellsèn, Tom N. Grossmann, Alleyn T. Plowright, Eric Valeur, Malin Lemurell, Herbert Waldmann   +11 more
openalex   +1 more source

Natural products structure database LOTUS supplemented with predicted 13C NMR chemical shifts.

, 2022
Jean‐Marc Nuzillard
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

The Relationship of In Vitro Anti-Inflammatory and Antioxidant Activity with Total Phenolic and Flavonoids Content of Tithonia diversifolia Leaves Ethanolic Extract and Fractions

JPSCR: Journal of Pharmaceutical Science and Clinical Research
A previous study showed that Tithonia diversifolia ethanolic extract has antiproliferative properties against HeLa cervical cancer cells. It has also shown anti-inflammatory properties in vivo, one of the approaches to cancer chemoprevention.
Endah Puspitasari, Nuri Nuri, Siti Muslichah, Bawon Triatmoko, Dewi Dianasari   +4 more
doaj   +1 more source

Highest weights for truncated shifted Yangians and product monomial crystals

, 2019
Truncated shifted Yangians are a family of algebras which are natural quantizations of slices in the affine Grassmannian. We study the highest weight representations of these algebras.
Kamnitzer, Joel, Tingley, Peter, Webster, Ben, Weekes, Alex, Yacobi, Oded   +4 more
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

An ECD and NMR/DP4+ Computational Pipeline for Structure Revision and Elucidation of Diphenazine-Based Natural Products [PDF]

, 2023
Yihao Zhuang, Fei Yang, Arya Menon, James M. Song, Rosa V. Espinoza, Pamela J. Schultz, Amanda L. Garner, Ashootosh Tripathi   +7 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Modulation of muscle anabolism and gut microbiota by Polyporus umbellatus extract attenuates dexamethasone-induced muscle atrophy

Applied Biological Chemistry
To investigate the pharmacological mechanisms by extract of Polyporus umbellatus (PU) protects against dexamethasone (DEX)-induced muscle atrophy, focusing on its direct effects on muscle cell signaling, mitochondrial function, oxidative stress, and its ...
Nguyen Bao Ngoc, Subeen Kim, Hye-Young Youn, Huitae Min, Tam Thi Le, Mauliasari Intan Rizki, Dae Won Kim, Kwang Hyeon Cha, Young Tae Park, Sang Hoon Jung, Myungsuk Kim   +10 more
doaj   +1 more source