Comparative evaluation of methanol and water extracts: Antioxidant activity and total phenolic content of ten papuan medicinal plants [PDF]
BIO Web of ConferencesThe use of Papuan medicinal plants as traditional medicine is widespread, but comprehensive and systematic research on their antioxidant activity and phenolic content remains limited.
Santoso Bimo Budi +2 more
doaj +1 more source
Remodelling of the natural product fumagillol employing a reaction discovery approach [PDF]
, 2011 In the search for new biologically active molecules, diversity-oriented synthetic strategies break through the limitation of traditional library synthesis by sampling new chemical space. Many natural products can be regarded as intriguing starting points
Balthaser, Bradley R. +4 more
core +1 more source
Directed enzyme evolution: climbing fitness peaks one amino acid at a time [PDF]
, 2009 Directed evolution can generate a remarkable range of new enzyme properties. Alternate substrate specificities and reaction selectivities are readily accessible in enzymes from families that are naturally functionally diverse.
Arnold, Frances H., Tracewell, Cara A.
core +2 more sources
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Editorial: Advances in natural product chemistry: Yunnan University 100th anniversary. [PDF]
Front Chem, 2023 Chen W, Dong J, Panda SS.
europepmc +1 more source
Organocatalytic synthesis of axially chiral atropisomers [PDF]
, 2017 This review summarises the recent progress made in the organocatalytic synthesis of atropisomeric compounds. Methodologies based on dynamic kinetic resolution and direct access to BINOL-like biaryls are described.
Renzi, P.
core +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
FEBS Open Bio, EarlyView.Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Foeniculum vulgare Essential Oils: Chemical Composition, Antioxidant and Antimicrobial Activities [PDF]
, 2010 The essential oils from Foeniculum vulgare commercial aerial parts and fruits were isolated by hydrodistillation, with different distillation times (30 min, I h, 2 h and 3 h), and analyzed by GC and GC-MS. The antioxidant ability was estimated using four
Barroso, J. G. +6 more
core
Marine Natural Products in Medicinal Chemistry [PDF]
ACS Medicinal Chemistry Letters, 2018 An overview of the marine natural products (MNPs) field is shown, including an update of FDA-approved drugs and those in clinical trials that can be considered derivatives of MNPs. The importance of marine microorganisms in present studies and the application of emerging techniques and technologies to this field are highlighted.
openaire +2 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source