Results 101 to 110 of about 979,824 (352)

A Historical Overview of Natural Products in Drug Discovery

open access: yesMetabolites, 2012
Historically, natural products have been used since ancient times and in folklore for the treatment of many diseases and illnesses. Classical natural product chemistry methodologies enabled a vast array of bioactive secondary metabolites from terrestrial
Daniel A. Dias   +2 more
doaj   +1 more source

The Philosophy of Natural Product Chemistry [PDF]

open access: yesNature, 1955
The Structural Relations of Natural Products Being the First Weizmann Memorial Lectures, December, 1953. By Sir Robert Robinson. Pp. xii + 150. (Oxford: Clarendon Press; London: Oxford University Press, 1955.) 25s. net.
openaire   +2 more sources

Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo [PDF]

open access: yes, 2017
Marrying synthetic biology with synthetic chemistry provides a powerful approach toward natural product diversification, combining the best of both worlds: expediency and synthetic capability of biogenic pathways and chemical diversity enabled by organic
AD Roy   +41 more
core   +2 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Penerapan Metode Praktikum Berbasis Bahan Alam dalam Pembelajaran Kimia untuk Meningkatkan Hasil Belajar Siswa pada Materi Reaksi Redoks [PDF]

open access: yes, 2019
The purpose of this study was to determine the improvement in learning outcomes of class X students in East Halmahera 9 High School on redox reaction topic by using natural product praticum methods in chemistry learning.
Caroles, J. D. (Joice)   +2 more
core  

The Use of SASAMBO Culture in Learning Natural Product Chemistry to Support Traditional Health Tourism in Lombok and Sumbawa Islands [PDF]

open access: yes, 2020
The SASAMBO (Sasak, Samawa, Mbojo) tribe has a variety of medicinal plants. The abundance of SASAMBO tribal medicinal plants can be used in learning the natural product chemistry which are expected to support traditional health tourism on the islands of ...
Al Idrus, Syarifa Wahidah   +3 more
core   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

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