Results 11 to 20 of about 833,393 (296)
Future Directions for the Discovery of Natural Product-Derived Immunomodulating Drugs.
Pharmacological Research, 2022 Drug discovery from natural sources is going through a renaissance, having spent many decades in the shadow of synthetic molecule drug discovery, despite the fact that natural product-derived compounds occupy a much greater chemical space than those ...
C. Wainwright +19 more
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Natural product chemistry for drug discovery [PDF]
The Journal of Antibiotics, 2011 S. Hashimoto
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Cell Chemical Biology, 2021 Summary The translation of functionally active natural products into fully synthetic small molecule mimetics has remained an important process in medicinal chemistry.
Mai Luo +9 more
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The crystal structure of 13-(pyrazole-1-yl-4-carbonitrile)-matrine, C19H25N5O
Zeitschrift für Kristallographie - New Crystal Structures, 2021 C19H25N5O, monoclinic, P21 (no. 4), a = 16.0600(2) Å, b = 5.3992(1) Å, c = 19.8514(2) Å, β = 94.260(1)°, V = 1716.58(4) Å3, Z = 4, Rgt (F) = 0.0350, wRref(F2) = 0.0908, T = 100.00(10) K.
Li Jun-Jie +8 more
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Integrated Metabolomic–Genomic Workflows Accelerate Microbial Natural Product Discovery
Analytical Chemistry, 2022 The pairing of analytical chemistry with genomic techniques represents a new wave in natural product chemistry. With an increase in the availability of sequencing and assembly of microbial genomes, interrogation into the biosynthetic capability of ...
Nicole E. Avalon, A. Murray, B. Baker
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Indonesian Journal of Chemistry, 2010 Preliminary studies on Terong Belanda (C. betacea ) have been carried out in this investigation with an aim to examine the presence of an alkaloid in the fruit of Terong Belanda.
Fredryk Mandey +2 more
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Perylenequinones from an endophytic Alternaria sp. of Pinus ponderosa
Heliyon, 2018 The differential solvent extraction and further purification of fractions of endophytic Alternaria sp. isolated from Pinus ponderosa led to the isolation of further two perylenequinone compounds as 3,6,6a,9,10-pentahydroxy-7,8-epoxy-4-oxo-4,5,6,6a,6b,7,8,
Mudasir A. Tantry +7 more
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Isolation and characterization of starch from Limnophila aromatica
Heliyon, 2019 Starch is one of the digestible natural polymers found in vascular plants. This natural polymer is the primary source of polysaccharides to produce energy for humans.
Cynthia Wijaya +7 more
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Furan-site transformations of obacunone as potent insecticidal agents
Heliyon, 2018 Furan ring is a key pharmacophore for insecticidal activity of limoninoids. To develop natural-product-based insecticidal agents, a series of furan-site transformations (2, 3 and 3a–j) of obacunone were synthesized by selective bromination and following ...
Ping Xiang +5 more
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First Stereoselective Total Synthesis of (3)-De--methylbotryosphaeriodiplodin
Natural Product Communications, 2019 A simple and highly efficient first stereoselective total synthesis of a benzofused macrocyclic lactone, ( 3S,7R )-de- O -methylbotryosphaeriodiplodin has been accomplished utilizing Jacobson's kinetic resolution, Marouka asymmetric allylation, Stille ...
Jhillu S. Yadav +5 more
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