Results 31 to 40 of about 833,393 (296)
Zeitschrift für Kristallographie - New Crystal Structures, 2018 C20H34N4O, triclinic, P1 (no. 1), a = 7.8545(6) Å, b = 10.8802(9) Å, c = 12.3714(9) Å, α = 73.200(7)°, β = 75.372(6)°, γ = 71.091(7)°, V = 942.65(13) Å3, Z = 2, Rgt(F) = 0.0591, wRref(F2) = 0.1641, T = 293(2) K.
Cheng Xing-An +5 more
doaj +1 more source
Applications of the Pharmacophore Concept in Natural Product inspired Drug Design
Molecular Informatics, 2020 Pharmacophore‐based techniques are nowadays an important part of many computer‐aided drug design workflows and have been successfully applied for tasks such as virtual screening, lead optimization and de novo design.
T. Seidel +3 more
semanticscholar +1 more source
Open Chemistry, 2017 The current study supports the phytochemical screening, evaluation of antioxidant and enzyme inhibition potential and correlations between antioxidant activities and phenolics of Rumex dentatus (Family: Polygonaceae), Mentha spicata (Family: Lamiaceae ...
Raza Muhammad Asam +5 more
doaj +1 more source
Definitions, 2020 Amaryllidaceae alkaloids (AAs) are a unique class of specialized metabolites containing heterocyclic nitrogen bridging that play a distinct role in higher plants.
T. Jayawardena +4 more
semanticscholar +1 more source
Heliyon, 2019 Indonesian cassia (Cinnamomum burmannii Blume) is commonly used as a condiment. It reportedly contains a number of major phytochemical constituents such as trans-cinnamaldehyde and coumarin. Sappan wood (Caesalpinia sappan) is a native plant of Southeast
Aditya Sindu Sakti +2 more
doaj +1 more source
Natural product synthesis at the interface of chemistry and biology
Chemistry, 2014 Nature has evolved to produce unique and diverse natural products that possess high target affinity and specificity. Natural products have been the richest sources for novel modulators of biomolecular function.
Jiyong Hong
semanticscholar +1 more source
Nature CommunicationsLead halide perovskites are promising for artificial photosynthesis but suffer from aqueous instability. Here, we stabilize CsPbI3 quantum dots within a hydrophobic chlorine-functionalized covalent organic framework through multisite atomic-chlorine ...
Genping Meng +8 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Antibiofilm formation activity of lupinifolin isolated from Derris reticulata stems against Enterococcus faecalis [PDF]
Journal of HerbMed PharmacologyIntroduction: The biofilm formation capability of Enterococcus faecalis is one of the key virulence factors contributing to its multidrug resistance and therapeutic challenges.
Pawitra Pulbutr +3 more
doaj +1 more source