Results 41 to 50 of about 9,230,804 (307)

Recent advances in the use of vibrational chiroptical spectroscopic methods for stereochemical characterization of natural products

, 2015
Covering: 2000 to 2014 This review covers conformational and configurational assignments in natural product molecules using chiroptical spectroscopy reported over the last 15 years.
Da Silva Bolzani, Vanderlan [UNESP], Blanch, Ewan W., Batista, João M.   +2 more
core   +1 more source

Multisite atomic-chlorine-passivation stabilizes perovskite interfaces for efficient H2O2 photosynthesis from seawater

Nature Communications
Lead halide perovskites are promising for artificial photosynthesis but suffer from aqueous instability. Here, we stabilize CsPbI3 quantum dots within a hydrophobic chlorine-functionalized covalent organic framework through multisite atomic-chlorine ...
Genping Meng, Shuai Wei, Ning Li, Yuhui Yin, Bin Dong, Shihao Sun, Guowen Hu, Hao Wang, Baodui Wang   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Functional Diversification and Structural Origins of Plant Natural Product Methyltransferases

, 2022
In plants, methylation is a common step in specialized metabolic pathways, leading to a vast diversity of natural products. The methylation of these small molecules is catalyzed by S-adenosyl-l-methionine (SAM)-dependent methyltransferases, which are ...
Stephanie Provenzano, Sara-Alexis Jarecki, Vonny Salim, Audrey Lashley, Ryan Miller, Paul Erba   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The crystal structure of the Matrine derivative: 12-(1H-indol-1-yl)dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one hydrate, C23H29N3O

Zeitschrift für Kristallographie - New Crystal Structures, 2017
C23H29N3O, orthorhombic P212121 (no. 19), a = 8.62130(10) Å, b = 18.25770(10) Å, c = 25.6873(2) Å, V = 4043.31(6) Å3, Z = 8, Rgt(F) = 0.0305, wRref(F2) = 0.0807, T = 293(2) K.
Xing-An Cheng, Zhan-Mei Liu, Wei-Xin Liang, Bo Wu, Xu-Hong Jiang   +4 more
doaj   +1 more source

Antibiofilm formation activity of lupinifolin isolated from Derris reticulata stems against Enterococcus faecalis [PDF]

Journal of HerbMed Pharmacology
Introduction: The biofilm formation capability of Enterococcus faecalis is one of the key virulence factors contributing to its multidrug resistance and therapeutic challenges.
Pawitra Pulbutr, Kridsanun Seelakot, Nicharee Kumphupong, Sakulrat Rattanakiat   +3 more
doaj   +1 more source

Comprehensive Characterization of Chemical Composition and Antioxidant Activity of Lignan-Rich Coniferous Knotwood Extractives

Antioxidants, 2022
A knotwood of coniferous trees containing large amounts of polyphenolic extractives is considered a promising industrial-scale source of lignans possessing antioxidant properties and other bioactivities.
Nikolay V. Ul’yanovskii, Aleksandra A. Onuchina, Anna V. Faleva, Natalia S. Gorbova, Dmitry S. Kosyakov   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source