Results 81 to 90 of about 1,020,429 (254)

The Philosophy of Natural Product Chemistry [PDF]

open access: yesNature, 1955
The Structural Relations of Natural Products Being the First Weizmann Memorial Lectures, December, 1953. By Sir Robert Robinson. Pp. xii + 150. (Oxford: Clarendon Press; London: Oxford University Press, 1955.) 25s. net.
openaire   +2 more sources

Organocatalytic synthesis of axially chiral atropisomers [PDF]

open access: yes, 2017
This review summarises the recent progress made in the organocatalytic synthesis of atropisomeric compounds. Methodologies based on dynamic kinetic resolution and direct access to BINOL-like biaryls are described.
Renzi, P.
core   +1 more source

Active invasion of bacteria into living fungal cells

open access: yeseLife, 2014
The rice seedling blight fungus Rhizopus microsporus and its endosymbiont Burkholderia rhizoxinica form an unusual, highly specific alliance to produce the highly potent antimitotic phytotoxin rhizoxin.
Nadine Moebius   +4 more
doaj   +1 more source

Remodelling of the natural product fumagillol employing a reaction discovery approach [PDF]

open access: yes, 2011
In the search for new biologically active molecules, diversity-oriented synthetic strategies break through the limitation of traditional library synthesis by sampling new chemical space. Many natural products can be regarded as intriguing starting points
Balthaser, Bradley R.   +4 more
core   +1 more source

A Historical Overview of Natural Products in Drug Discovery

open access: yesMetabolites, 2012
Historically, natural products have been used since ancient times and in folklore for the treatment of many diseases and illnesses. Classical natural product chemistry methodologies enabled a vast array of bioactive secondary metabolites from terrestrial
Daniel A. Dias   +2 more
doaj   +1 more source

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]

open access: yes, 2017
Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E   +3 more
core   +2 more sources

The crystal structure of a matrine derivative, 13-(4-Cl-pyrrole)-matrine, C18H26ClN4O

open access: yesZeitschrift für Kristallographie - New Crystal Structures, 2019
C18H26ClN4O, orthorhombic, P212121 (no. 19), a = 5.3476(1) Å, b = 14.4068(2) Å, c = 22.3285(4) Å, V = 1720.23(5) Å3, Z = 4, Rgt(F) = 0.0328, wRref(F2) = 0.0774, T = 100 K.
Jing-Min Ye   +5 more
doaj   +1 more source

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