Results 51 to 60 of about 39,942,250 (334)

DISCIPLINING RELATIVISM AND TRUTH

open access: yesZygon, 1989
. Imre Lakatos's philosophy of science can provide helpful leads for theological methodology, but only when mediated by the disciplines that lie between the natural sciences and theology.
doaj   +2 more sources

Integration of Mathematical and Natural-Science Knowledge in School Students’ Project-Based Activity

open access: yes, 2017
New educational standards implementation prioritizes the projective beginning of training in school education. Therefore, consideration of educational activity only as the process of obtaining ready knowledge should be abandoned.
Olga L. Luneeva, V. Zakirova
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

GIScience and remote sensing in natural resource and environmental research: Status quo and future perspectives

open access: yesGeography and Sustainability, 2021
Geographic information science (GIScience) and remote sensing have long provided essential data and methodological support for natural resource challenges and environmental problems research.
T. Pei   +9 more
semanticscholar   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Women in life science disciplines

open access: yes, 2002
The breakdown of the life science disciplines within the College of Life Sciences and Agriculture at the University of New Hampshire allowed us to establish the graduation patterns of men and women within the respective disciplines.
Douce, Lorraine D.   +2 more
core   +1 more source

Materials science in the era of large language models: a perspective [PDF]

open access: yesDigital Discovery
Large Language Models (LLMs) have garnered considerable interest due to their impressive natural language capabilities, which in conjunction with various emergent properties make them versatile tools in workflows ranging from complex code generation to ...
Ge Lei, R. Docherty, S. Cooper
semanticscholar   +1 more source

PROFESSIONAL COMPETENCES OF NATURAL SCIENCE TEACHER DISCIPLINES IN THE MODERN SCHOOL

open access: yesТHE SOURCES OF PEDAGOGICAL SKILLS, 2019
The current situation in education reflects the real picture of the transition to a post-industrial society, the value of which is competence and competence. Until recently, the concept of competence and competence was associated with higher professional education, where specific methods of training specialists were born: task, project, contextual, and
MARTSENYUK, T., SHCHERBAN, M.
openaire   +3 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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