Results 61 to 70 of about 39,942,250 (334)
Beginning again. The task of design research
Joelho, 2013 Among architects and educators today the proposal for design research is generally understood as follows: the design of buildings is not only a professional practice but also a form of inquiry, a member of the growing family of research ...
David Leatherbarrow
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
THE METHOD OF INFORMATION MODELING AS A TEACHING TOOL AND A TOOL OF UNDERSTANDING REALITY
Вестник Мининского университета, 2017 ARTICLE WITHDRAWNThis article analyzes the role of information modeling as a universal approach to the study of complex objects in the study of natural sciences disciplines (computer science, mathematics, physics).
M. L. Gruzdeva
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Diversity, equity, and inclusion in natural science education: A review of literature
Natural Sciences EducationDiversity, equity, and inclusion (DEI) are relevant in societal discourse and have implications for educators in natural sciences disciplines. A synthesis of DEI research in these disciplines is necessary to identify opportunities to strengthen ...
Catlin M. Goodwin, R. McKendree
semanticscholar +1 more source
, 2020 © 2018 Authors. The actuality of the problem stated in the article is due to the fact that the level of professional competence of future teachers of the natural- science subjects largely depends on the quality of mathematical training, which is largely ...
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Transdisciplinarity: two preliminary issues
The Journal for Transdisciplinary Research in Southern Africa, 2013 Any discussion about transdisciplinarity presupposes some sort of recognition of the scientific disciplines and some agreement on how they are or should be grouped or classified.
Renato Coletto
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Postdigital science and education
Communiars. Revista de Imagen, Artes y Educación Crítica y Social, 2018 We are increasingly no longer in a world where digital technology and media is separate, virtual, ‘other’ to a ‘natural’ human and social life. This has inspired the emergence of a new concept—‘the postdigital’— which is slowly but surely gaining ...
P. Jandrić +5 more
semanticscholar +1 more source