Results 71 to 80 of about 728,426 (302)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Expanding new niche for DRJ: Evolution of an institutional scholarly publication
Davao Research Journal, 2015 The Davao Journal (DRJ) is in a transition period of expansion in its scope, types of manuscript accepted, manuscript preparation, and ethical standards. This expansion aims to cater more diverse manuscripts in various disciplines both in Natural Science
Emily Antonio
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Mediterranean Journal of Social Sciences, 2015 In work experience, the realization of interdisciplinary integration of disciplines of natural science and technical blocks when training graduates of the construction direction in technical college is considered. Formation of professional competence of the Bachelor is one of the strategic tasks of higher education institution that decision is possible
D.K. Afanasova, Z.Z. Utyaganova
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The educational standards of the third generation and teaching educational discipline "Concepts of modern natural science" [PDF]
, 2014 В данной работе рассматриваются место и роль вспомогательных учебных дисциплин в современной концепции образования. Рассказывается об особенностях преподавания учебной дисциплины «Концепции современного естествознания».This paper discusses the place and ...
Doroshenko, V. A. +3 more
core
Management of Education, 2022 Ценностное, нравственное отношение к природе, по нашему заключению, предполагает, что природный объект или явление обладает определенными свойствами, которые позволяют признать его полезность или вредность. Однако не все, что полезно в определенный момент отдельному индивиду, одновременно является благом вообще и пользой для всех. Утилитарное отношение
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Agricultural economics is a field of applied economics. Its scope and its relationship to other social and natural science disciplines has changed over time in response to (a) the social, economic and technical changes impinging on the agricultural ...
Ruttan, Vernon W.
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The Education and science journal, 2023 Introduction. Globally, there are integrated natural science disciplines in the training programmes for humanities students in many universities in order to overcome the gap between the humanitarian-artistic and natural-science cultures, to form a holistic view of the physical world and the basics of technology among university graduates, to equip ...
openaire +2 more sources