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Natural Knockouts: Natural Selection Knocked Out [PDF]
In functional genomics studies, research is dedicated to unveiling the function of genes using gene-knockouts, model organisms in which a gene is artificially inactivated. The idea is that, by knocking out the gene, the provoked phenotype would inform us
Peter Borger
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Natural Induction: Spontaneous Adaptive Organisation without Natural Selection [PDF]
Evolution by natural selection is believed to be the only possible source of spontaneous adaptive organisation in the natural world. This places strict limits on the kinds of systems that can exhibit adaptation spontaneously, i.e., without design ...
Christopher L. Buckley +5 more
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Background: Synthetic engineering of bacteria to produce industrial products is a burgeoning field of research and application. In order to optimize genome design, designers need to understand which genes are essential, which are optimal for growth, and ...
Granger Sutton +6 more
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Background: Synthetic engineering of bacteria to produce industrial products is a burgeoning field of research and application. In order to optimize genome design, designers need to understand which genes are essential, which are optimal for growth, and ...
Granger Sutton +6 more
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Background: Wall teichoic acid (WTA) genes are essential for production of cell walls in gram-positive bacteria and necessary for survival and variability in the cassette has led to recent antibiotic resistance acquisition in pathogenic bacteria ...
Gary B. Fogel +6 more
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Adaptations Accumulated under Prolonged Resource Exhaustion Are Highly Transient
Many nonsporulating bacterial species can survive for years within exhausted growth media in a state termed long-term stationary phase (LTSP). We have been carrying out evolutionary experiments aimed at elucidating the dynamics of genetic adaptation ...
Sarit Avrani +2 more
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All aboard the 'Elephant Express', a practical solution for human-elephant coexistence
One of the most significant challenges for elephant conservation is managing negative interactions that occur where people and elephants use the same space and compete for resources.
Anna Songhurst +9 more
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Natural process – Natural selection [PDF]
Life is supported by a myriad of chemical reactions. To describe the overall process we have formulated entropy for an open system undergoing chemical reactions. The entropy formula allows us to recognize various ways for the system to move towards more probable states. These correspond to the basic processes of life i.e. proliferation, differentiation,
Vivek, Sharma, Arto, Annila
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Path-dependent selection—a bridge between natural selection and neutral selection
Path-dependent selection follows the premise of complete symmetry in the neutral theory of selection; mutations in the natural world are entirely based on statistical randomness, lack directionality, and thus do not exhibit differences in fitness.
Rui-Wu Wang +9 more
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