Results 121 to 130 of about 95,304 (243)

Novel MYL1 Intron Variant With Expanded Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital myopathy‐14 (CMYO14) is an ultrarare autosomal recessive disorder caused by biallelic variants in MYL1, with only four patients reported to date. We describe what is likely the fifth reported patient, a neonate with severe hypotonia, respiratory insufficiency, and skeletal anomalies showing distinct histological changes of skeletal ...
Maria Barington, Marie Balslev‐Harder, Thomas Krag, Thomas van Overeem Hansen, Camilla Bernt Wulff, Ulrik Lausten‐Thomsen, Tina Duelund Hjortshøj, Elsebet Østergaard   +7 more
wiley   +1 more source

Regularity of Mine Gas Flow Disaster Induced by Gas Natural Ventilation Pressure after Coal and Gas Outbursts. [PDF]

ACS Omega, 2021
Yu J, Li Z, Liu Y, Dong Z, Sun Y.
europepmc   +1 more source

Isovolumic relaxation strain imaging is an accurate and sensitive approach for detection of active diastolic dysfunction: A preclinical study

Animal Models and Experimental Medicine, EarlyView.
A modified approach was developed to accurately identify the isovolumetric relaxation time (IVRT) using an apical three‐chamber view. Compared with conventional echocardiography, isovolumic relaxation strain imaging (IVSI) helps to detect the earlier alternations of diastolic function in transverse aortic constriction (TAC) mice.
Jingjing Liang, Juncheng Wang, Jun Cheng, Yanggan Wang   +3 more
wiley   +1 more source

Interaction between Natural and Ventilated Cavitation around a Base Ventilated Hydrofoil

Journal of Applied Fluid Mechanics, 2019
In more recent years, supercavitation has attracted intensive attention due to its potentials in drag reduction for underwater vehicles. Ventilation is acknowledged as an efficient way to enhance cavitation when vehicles work under low speed.
H. Zhou, M. Xiang, W. Zhang, X. Xu, K. Zhao, S. Zhao   +5 more
doaj  

Dataset of the EnergyPlus model used in the assessment of natural ventilation potential through building simulation. [PDF]

Data Brief, 2021
Sakiyama NRM, Mazzaferro L, Carlo JC, Bejat T, Garrecht H.   +4 more
europepmc   +1 more source

Methylophiopogonanone a attenuates pulmonary fibrosis by inhibiting SPP1‐mediated macrophage polarization via the PI3K/Akt pathway

Animal Models and Experimental Medicine, EarlyView.
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang, Tian Li, Weiran Jia, Dingjie Xu, Liangdan Sun, Yanlei Ge, Yiwei Shi, Hong Xu, Xudong Song, Fuyu Jin, Na Mao   +10 more
wiley   +1 more source

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

Impact of natural ventilation on exposure to SARS-CoV 2 in indoor/semi-indoor terraces using CO₂ concentrations as a proxy. [PDF]

J Build Eng, 2022
Rivas E, Santiago JL, Martín F, Martilli A.   +3 more
europepmc   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Analysis of Impact of Natural Ventilation Strategies in Ventilation Rates and Indoor Environmental Acoustics Using Sensor Measurement Data in Educational Buildings. [PDF]

Sensors (Basel), 2021
de la Hoz-Torres ML, Aguilar AJ, Ruiz DP, Martínez-Aires MD.   +3 more
europepmc   +1 more source