Results 51 to 60 of about 17,731 (225)

FGF14 modulates resurgent sodium current in mouse cerebellar Purkinje neurons

eLife, 2014
Rapid firing of cerebellar Purkinje neurons is facilitated in part by a voltage-gated Na+ (NaV) ‘resurgent’ current, which allows renewed Na+ influx during membrane repolarization.
Haidun Yan, Juan L Pablo, Chaojian Wang, Geoffrey S Pitt   +3 more
doaj   +1 more source

1D Pre‐Acquisition Navigator Correcting Respiratory‐Induced Field Fluctuations in Multi‐Echo Gradient‐Echo Imaging of the Thoracic Spinal Cord

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose In the spinal cord (SC), multi‐echo gradient echo (ME‐GRE) increases gray (GM) and white matter (WM) contrast and improves sensitivity to lesions in people with multiple sclerosis (pwMS). However, SC ME‐GRE is susceptible to breathing‐induced field fluctuations, causing ghosting artifacts and signal loss.
Alicia E. Cronin, Alexandre D'Astous, Nathan Williams, Antoine Guénette, Aimee Salakhov, Seth Stubblefield, Colin D. McKnight, Lipika Narisetti, Subramaniam Sriram, Seth A. Smith, Ryan K. Robison, Guillaume Gilbert, Julien Cohen‐Adad, Kristin P. O'Grady   +13 more
wiley   +1 more source

Stabilization of Cu Species in UiO‐66 Metal–Organic Framework for CO2‐to‐Methanol: Insights From Operando X‐ray and Electron Microscopy Studies

Small, EarlyView.
This study reveals how a zirconium‐based metal–organic framework (UiO‐66) stabilizes copper species during CO2 hydrogenation to methanol. Operando X‐ray spectroscopy, electron microscopy, and theory show that zinc promotes highly dispersed copper and suppresses particle growth, while the framework dynamically responds to reaction intermediates.
Anna Liutkova, Fabio André Peixoto Esteves, Marianela López Romero, Margareth S. Baidun, Anastasia Molokova, Davide Salusso, Kirill A. Lomachenko, Andrea Testino, Alexander A. Kolganov, Evgeny A. Pidko, Emiliya Poghosyan, Marco Ranocchiari   +11 more
wiley   +1 more source

Veratridine-Induced Oscillations in Nav 1.7 but Not Nav 1.5 Sodium Channels Are Revealed by Membrane Potential Sensitive Dye

Membranes
Voltage-gated sodium channels (Navs) are critical for membrane potential depolarisation in cells, with especially important roles in neuronal and cardiomyocyte membranes.
Sarah C. R. Lummis, Samantha C. Salvage, Christopher L.-H. Huang, Antony P. Jackson   +3 more
doaj   +1 more source

A Case-Controlled Study Evaluating the Effect of Cone Beam CT (O-Arm) Imaging and Navigation on Pedicle Screw Placement in Adult Spinal Surgery

Global Spine Journal, 2015
Introduction Intraoperative CT and navigation systems (NAV) may provide an opportunity to improve precision and accuracy of pedicle screw placement, and in so doing, improve patient outcomes.
Jason Strelzow, Danny Mendelsohn, Nicolas Dea, Mélissa Nadeau, Marcel Dvorak, Charles Fisher, John Street   +6 more
doaj   +1 more source

The Nav channel bench series: Plasmid preparation

MethodsX, 2014
Research involving recombinant voltage-gated sodium (Nav) channels has unique challenges. Multiple factors contribute, but undoubtedly at the top of the list is these channels’ DNA instability.
Daniel H. Feldman, Christoph Lossin
doaj   +1 more source

Microfluidic Sample Compartmentalization for Biomolecular Concentration Quantification Using a Nanopore Sensor

Small Methods, EarlyView.
We compartmentalize samples into picoliter volumes using a microfluidic device, allowing us to determine biomolecular concentration by counting molecules to depletion within a known volume without calibration. By integrating a nanopore sensor for this counting process, we also obtain real‐time data on the size, shape, and conformation of each ...
Morteza Safari, Juliana Chawich, Ali Najafi Sohi, Martin Charron, Vincent Tabard‐Cossa, Michel Godin   +5 more
wiley   +1 more source

Aktivitetsplan som styringsverktøy

Søkelys på Arbeidslivet, 2018
Artikkelen undersøker hvordan institusjonelle føringer bidrar til å forme NAV-ansattes arbeid og bruk av aktivitetsplanen i arbeid med arbeidsavklaringsprosesser. Avklaringsprosessene som undersøkes her, gjelder unge mennesker med psykiske lidelser.
Hilde Åsheim
doaj   +1 more source

Contagion and Spillover Effects of the Chinese Housing Crisis on the China‐Focused ETFs Trading in the United States

Pacific Economic Review, EarlyView.
ABSTRACT This study investigates the impact of China's recent real estate crisis, stemming from Evergrande's struggles, on the return and risk profiles of US‐listed exchange traded funds (ETFs) tracking Chinese stock market indexes. Analysing 26 funds from February 2, 2018 to December 31, 2024, we first employ a VAR model to assess contagion and ...
Gerasimos Rompotis, Spyros Papathanasiou, Drosos Koutsokostas   +2 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source