Results 61 to 70 of about 17,731 (225)

Fra serviceorientert kompetanse til samspillskompetanse? En analyse av kvalifikasjonskrav til Nav-veiledere

Norsk Statsvitenskapelig Tidsskrift
Denne artikkelen presenterer funn fra en kvalitativ innholdsanalyse som sammenligninger stillingsannonser i Nav fra 2008–2009 med stillingsannonser i 2022–2023.
Inge Hermanrud
doaj   +1 more source

Subtype Specificity of β-Toxin Tf1a from Tityus fasciolatus in Voltage Gated Sodium Channels

Toxins, 2018
Scorpion venoms are a complex mixture of components. Among them the most important are peptides, which presents the capacity to interact and modulate several ion channel subtypes, including voltage-gated sodium channels (NaV).
Daniel Oliveira da Mata, Diogo Vieira Tibery, Leandro Ambrósio Campos, Thalita Soares Camargos, Steve Peigneur, Jan Tytgat, Elisabeth Ferroni Schwartz   +6 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

Effectiveness of Problem-based Learning (PBL) on Maritime Courses in a Blended Learning Modality [PDF]

TransNav
This study aimed to determine the effectiveness of problem-based learning (PBL) on identified courses in improving the performance of maritime students. This study utilized pretest-posttest non-equivalent group design.
Roderick Germo, V.S. Tan, A.F. Casaáare
doaj   +1 more source

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

Fund Age, BI Rate, Exchange Rate, Dan Jakarta Islamic Index Pada Net Asset Value Di Islamic Equity Mutual Fund Indonesia

Jurnal Manajemen, 2019
Net Asset Value (NAV) of islamic equity mutual fund is a benchmark to determine the development of islamic equity mutual fund. There are many factors that is influence NAV of Islamic equity mutual fund such as macroeconomic factors as well as internal ...
Darmawan Darmawan
doaj   +1 more source

Seizures in children with Dravet syndrome in extreme heat: A qualitative study of parental perspectives

Developmental Medicine &Child Neurology, EarlyView.
Perspectives of parents of children with Dravet syndrome indicate that extreme heat and high temperatures exacerbate epileptic seizures, introduce new seizure triggers, and require the adoption of specific seizure‑management strategies. Abstract Aim To describe parental perspectives on how heatwaves and high ambient temperatures influence seizure ...
Angel Aledo‐Serrano, José Ángel Aibar, Domingo Palacios‐Ceña, Maria Salcedo‐Perez‐Juana, Maria Palacios‐Ceña, Simona Giorgi, Manuel Lorenzo‐Dieguez, Sanjay M Sisodiya, Cristina García‐Bravo   +8 more
wiley   +1 more source

Jobbspesialister i NAV

, 2020
Fram til 2016 har NAV kjøpt størsteparten av oppfølgingstjenester til arbeidsinkludering hos eksterne tjenesteleverandører. I Meld. St. 33 (2015–2016) annonserte Arbeids- og sosialdepartementet at NAV i framtida skal tilby en betraktelig del av disse oppfølgingstjenestene i egen regi.
Schönfelder, Walter, Arntzen, Cathrine, Johansen, Thomas, Munkejord, Mai Camilla   +3 more
openaire   +1 more source

Measuring Thematic Funds Performance via an Approach Based on Observable and Latent Factors

European Financial Management, EarlyView.
ABSTRACT This paper investigates whether thematic equity funds deliver abnormal performance relative to conventional global equity funds. Using Fama‐French models augmented with latent factors, we estimate fund‐level alphas, and apply the false discovery rate methodology to an estimated three‐group mixture distribution, separating good, null and bad ...
Maria Debora Braga, Gianmarco Vacca, Maria Zoia   +2 more
wiley   +1 more source