Results 61 to 70 of about 184,365 (253)

A Case-Controlled Study Evaluating the Effect of Cone Beam CT (O-Arm) Imaging and Navigation on Pedicle Screw Placement in Adult Spinal Surgery

Global Spine Journal, 2015
Introduction Intraoperative CT and navigation systems (NAV) may provide an opportunity to improve precision and accuracy of pedicle screw placement, and in so doing, improve patient outcomes.
Jason Strelzow, Danny Mendelsohn, Nicolas Dea, Mélissa Nadeau, Marcel Dvorak, Charles Fisher, John Street   +6 more
doaj   +1 more source

Gain control with A-type potassium current: IA as a switch between divisive and subtractive inhibition [PDF]

, 2018
Neurons process information by transforming barrages of synaptic inputs into spiking activity. Synaptic inhibition suppresses the output firing activity of a neuron, and is commonly classified as having a subtractive or divisive effect on a neuron's ...
Goldwyn, Joshua H, Slabe, Bradley R, Terman, David, Travers, Joseph B   +3 more
core   +4 more sources

ISAC-Nav

, 2022
En los últimos años, muchas aplicaciones y sistemas requieren de una herramienta de geolocalización para su correcto funcionamiento. Actualmente, el GPS es el sistema de posicionamiento global de referencia, pero no el único, ya que cada vez hay más sistemas alternativos en el mercado.
openaire   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Assessment of verbal comprehension and non-verbal reasoning when standard response mode is challenging: A comparison of different response modes and an exploration of their clinical usefulness

Cogent Psychology, 2017
Objective: Assessment of cognition is important for providing children with developmentally appropriate interventions. Often children with severe speech and motor disorders are not assessed, as standardized assessment is perceived as challenging.
Ramune Kurmanaviciute, Kristine Stadskleiv   +1 more
doaj   +1 more source

Hvorfor lykkes ikke NAV-kontorene med å jobbe mer arbeidsrettet?

Søkelys på Arbeidslivet, 2016
Sammendrag En sentral forklaring på NAVs manglende måloppnåelse om flere i arbeid og aktivitet og færre på trygd har vært omstillingsprosessen med den lokale etableringen av NAV-kontorene.
Knut Fossestøl, Eric Breit, Elin Borg
doaj   +1 more source

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh, Zahra Haghighijoo, Akanksha Gurtu, Nolan M. Dvorak, Timothy J. Baumgartner, Nana A. Goode, Jully Singh, Matteo Bernabucci, Adam T. Szafran, Michael J. Bolt, Michael A. Mancini, Natalie M. Dvorak, Marijn Lijffijt, Zhiqing Liu, Yu Xue, Alyssa K. Thomas, Alejandro Villasante‐Tezanos, Balaji Krishnan, Jia Zhou, Fernanda Laezza   +19 more
wiley   +1 more source

Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling

eLife, 2020
Calcium ions (Ca2+) are essential for many cellular signaling mechanisms and enter the cytosol mostly through voltage-gated calcium channels. Here, using high-speed Ca2+ imaging up to 20 kHz in the rat layer five pyramidal neuron axon we found that ...
Naomi AK Hanemaaijer, Marko A Popovic, Xante Wilders, Sara Grasman, Oriol Pavón Arocas, Maarten HP Kole   +5 more
doaj   +1 more source

School‐to‐Work Transitions Among Out‐of‐Home Care and Aftercare Experienced Individuals: A Norwegian National Register Study

Child &Family Social Work, EarlyView.
ABSTRACT Individuals with child protection service (CPS) experience face increased risks of social exclusion and unemployment. Employment is vital for both financial stability and health. Teenagers in out‐of‐home care (OHC) are particularly vulnerable to unemployment.
Trine Holten, Kirsti Klem Valset
wiley   +1 more source

Veratridine-Induced Oscillations in Nav 1.7 but Not Nav 1.5 Sodium Channels Are Revealed by Membrane Potential Sensitive Dye

Membranes
Voltage-gated sodium channels (Navs) are critical for membrane potential depolarisation in cells, with especially important roles in neuronal and cardiomyocyte membranes.
Sarah C. R. Lummis, Samantha C. Salvage, Christopher L.-H. Huang, Antony P. Jackson   +3 more
doaj   +1 more source