Results 71 to 80 of about 35,363 (287)

CD86‐Positive Mature Tertiary Lymphoid Structures Are Associated With CD8+ T‐Cell Infiltration and Favorable Clinical Outcomes in Pancreatic Ductal Adenocarcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
CD86‐positive mature tertiary lymphoid structures were associated with increased intratumoral CD8+ T‐cell infiltration, a higher proportion of Granzyme B‐expressing CD8+ T cells in an exploratory analysis, and favorable clinical outcomes in pancreatic ductal adenocarcinoma.
Takaomi Seki   +10 more
wiley   +1 more source

Interaction of Nucleolin with the Fusion Protein of Avian Metapneumovirus Subgroup C Contributes to Viral Replication

open access: yesViruses, 2022
Avian metapneumovirus subgroup C (aMPV/C) is highly pathogenic to various avian species with acute respiratory tract clinicopathology and/or drops in egg production.
Dedong Wang   +8 more
doaj   +1 more source

Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG

open access: yesInternational journal of pharmaceutics, 2017
Cancer cells increase their metabolism to produce the energy and biomolecules necessary for growth and proliferation. Thus, energy metabolism pathways may serve as targets for anti-cancer therapy. NCL-240 is a second generation anti-cancer drug belonging
Bhushan S. Pattni   +5 more
semanticscholar   +1 more source

NCLs and ER: A stressful relationship

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017
The Neuronal Ceroid Lipofuscinoses (NCLs, Batten disease) are a group of inherited neurodegenerative disorders with variable age of onset, characterized by the lysosomal accumulation of autofluorescent ceroid lipopigments. The endoplasmic reticulum (ER) is a critical organelle for normal cell function. Alteration of ER homeostasis leads to accumulation
Marotta, Davide   +2 more
openaire   +3 more sources

Low power circuit design using NCL based asynchronous method [PDF]

open access: yes, 2021
The null convention logic (NCL) based circuit design methodology eliminates the problems related to noise, clock tree, electromagnetic interference and also reduces significant power consumption.
Hoang, Trang   +2 more
core   +1 more source

TGF-β1 signalling in Alzheimer’s pathology and cytoskeletal reorganization: a specialized Tau perspective

open access: yesJournal of Neuroinflammation, 2023
Microtubule-associated protein, Tau has been implicated in Alzheimer's disease for its detachment from microtubules and formation of insoluble intracellular aggregates within the neurons.
Mahima Kapoor   +1 more
doaj   +1 more source

A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy

open access: yesOncoTarget, 2016
Breast cancer is the most common cancer in women worldwide. A new promising anti-cancer therapy involves the use of monoclonal antibodies specific for target tumor-associated antigens (TAAs).
Chiara D’Avino   +8 more
semanticscholar   +1 more source

Characterization of phosphorylation-deficient NCL-mutant.

open access: yes, 2014
(A) Targeting the consensus CK2 sites in NCL: The modular structure of NCL protein is shown, indicating the positions of principal domains. The six consensus CK2 sites (all serine) that were mutated to alanine in the 6/S*A construct are denoted by ...
Xin Li (51274)   +8 more
core   +1 more source

NCL script for Fig S3

open access: yes, 2019
NCL scripts for ...
Mark England (8067878)
core   +1 more source

Silk fibroin micro-particle scaffolds with superior compression modulus and slow bioresorption for effective bone regeneration

open access: yesScientific Reports, 2018
Silk fibroin (SF), a natural polymer produced by Bombyx mori silkworms, has been extensively explored to prepare porous scaffolds for tissue engineering applications.
Anuya Nisal   +7 more
doaj   +1 more source

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