Results 71 to 80 of about 35,363 (287)
CD86‐positive mature tertiary lymphoid structures were associated with increased intratumoral CD8+ T‐cell infiltration, a higher proportion of Granzyme B‐expressing CD8+ T cells in an exploratory analysis, and favorable clinical outcomes in pancreatic ductal adenocarcinoma.
Takaomi Seki +10 more
wiley +1 more source
Avian metapneumovirus subgroup C (aMPV/C) is highly pathogenic to various avian species with acute respiratory tract clinicopathology and/or drops in egg production.
Dedong Wang +8 more
doaj +1 more source
Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG
Cancer cells increase their metabolism to produce the energy and biomolecules necessary for growth and proliferation. Thus, energy metabolism pathways may serve as targets for anti-cancer therapy. NCL-240 is a second generation anti-cancer drug belonging
Bhushan S. Pattni +5 more
semanticscholar +1 more source
NCLs and ER: A stressful relationship
The Neuronal Ceroid Lipofuscinoses (NCLs, Batten disease) are a group of inherited neurodegenerative disorders with variable age of onset, characterized by the lysosomal accumulation of autofluorescent ceroid lipopigments. The endoplasmic reticulum (ER) is a critical organelle for normal cell function. Alteration of ER homeostasis leads to accumulation
Marotta, Davide +2 more
openaire +3 more sources
Low power circuit design using NCL based asynchronous method [PDF]
The null convention logic (NCL) based circuit design methodology eliminates the problems related to noise, clock tree, electromagnetic interference and also reduces significant power consumption.
Hoang, Trang +2 more
core +1 more source
Microtubule-associated protein, Tau has been implicated in Alzheimer's disease for its detachment from microtubules and formation of insoluble intracellular aggregates within the neurons.
Mahima Kapoor +1 more
doaj +1 more source
A novel fully human anti-NCL immunoRNase for triple-negative breast cancer therapy
Breast cancer is the most common cancer in women worldwide. A new promising anti-cancer therapy involves the use of monoclonal antibodies specific for target tumor-associated antigens (TAAs).
Chiara D’Avino +8 more
semanticscholar +1 more source
Characterization of phosphorylation-deficient NCL-mutant.
(A) Targeting the consensus CK2 sites in NCL: The modular structure of NCL protein is shown, indicating the positions of principal domains. The six consensus CK2 sites (all serine) that were mutated to alanine in the 6/S*A construct are denoted by ...
Xin Li (51274) +8 more
core +1 more source
Silk fibroin (SF), a natural polymer produced by Bombyx mori silkworms, has been extensively explored to prepare porous scaffolds for tissue engineering applications.
Anuya Nisal +7 more
doaj +1 more source

