Results 61 to 70 of about 25,091 (203)

Dissecting the tRNA Fragment tRF3E–Nucleolin Interaction: Implications in Breast Cancer

open access: yesBiomolecules
Nucleolin (NCL), an RNA-binding protein which regulates critical cellular processes, is frequently dysregulated in human cancers, including breast cancer, making it an attractive therapeutic target.
Maurizio Falconi   +14 more
doaj   +1 more source

Molecular networking in the neuronal ceroid lipofuscinoses: insights from mammalian models and the social amoeba Dictyostelium discoideum

open access: yesJournal of Biomedical Science, 2020
The neuronal ceroid lipofuscinoses (NCLs), commonly known as Batten disease, belong to a family of neurological disorders that cause blindness, seizures, loss of motor function and cognitive ability, and premature death.
Robert J. Huber
doaj   +1 more source

Proteomic Characterization of AS1411 Reveals ATP6AP1 as a Mediator of Triple‐Negative Breast Cancer Progression

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae   +6 more
wiley   +1 more source

NCl(a)自猝灭对NCl(a)/I激光性能的影响

open access: yes, 2004
The effect of NCl(a1Δ) self-annihilation on the production of NCl(a1Δ) and energy extraction of NCl(a1Δ)-I laser was simulated by means of a simplified continuous flow F-P resonator model.
唐书凯   +3 more
core  

Mapping the global threat of Mythimna separata (Walker) and its economic implications for Brazil's agriculture

open access: yesPest Management Science, EarlyView.
Global models identified high‐risk areas for Mythimna separata invasion, highlighting major economic vulnerability for Brazilian crops and guiding targeted prevention and management strategies. Abstract BACKGROUND Identifying high‐risk areas for the introduction of invasive alien species is particularly important for agricultural pests with a broad ...
Gabriel Dorotel da Silva Ferreira   +1 more
wiley   +1 more source

Asynchronous Circuit Design using New High Speed NCL Gates

open access: yes, 2014
The delay-insensitive Null Convention Logic (NCL) as one of innovative asynchronous logic design methodologies has many advantages of inherent robustness, power consumption, and easy design reuses. However, transistor-level topologies of conventional NCL
null Minsu Choi   +7 more
core   +1 more source

Monoalcohol‐Directed Shape Control in a Surfactant‐Free Gold Nanoplate Synthesis

open access: yesSmall Methods, EarlyView.
Surfactant‐free monoalcohol syntheses are advantageous in that they yield colloidal nanostructures that are free of persistent shape‐directing agents but at the expense of realizing only spherically‐shaped nanoparticles. In this work, this limitation is overcome using a low‐complexity light‐driven synthetic protocol yielding periodic arrays of gold ...
Brendan D. Nieukirk   +7 more
wiley   +1 more source

Performance Analysis And Optimisation Of Ncl Self-Timed Rings

open access: yes, 2003
A self-timed ring using NULL convention logic (NCL) is presented. An analytical method to evaluate the speed of NCL rings has been developed. The analytical predictions are verified by a Synopsys simulation and excellent agreement between the theoretical
DeMara, R. F., Kuang, W., Yuan, J. S.
core   +2 more sources

Parametric study of NCl(a(1)Delta) and NCl(b(1)Sigma) from the reaction of Cl/Cl-2/He+HN3/He

open access: yes, 2002
By means of a microwave generator, chlorine diluted by helium was dissociated to chlorine atoms that subsequently reacted with hydrogen azide to produce the excited states of NCl(a(1)Delta) and NCl(b(1)Sigma).
Yang, BL   +5 more
core   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng   +3 more
wiley   +1 more source

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