Results 1 to 10 of about 12,341 (216)
Expression of Nucleolin Affects Microtubule Dynamics.
PLoS ONE, 2016 Nucleolin is present in diverse cellular compartments and is involved in a variety of cellular processes from nucleolar structure and function to intracellular trafficking, cell adhesion and migration. Recently, nucleolin has been localized at the mature
Xavier Gaume +5 more
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Nucleolin, a shuttle protein promoting infection of human monocytes by Francisella tularensis.
PLoS ONE, 2010 BackgroundFrancisella tularensis is a highly virulent facultative intracellular bacterium, disseminating in vivo mainly within host mononuclear phagocytes. After entry into macrophages, F.
Monique Barel +2 more
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Structure-function analysis of nucleolin and ErbB receptors interactions.
PLoS ONE, 2009 BackgroundThe ErbB receptor tyrosine kinases and nucleolin are major contributors to malignant transformation. Recently we have found that cell-surface ErbB receptors interact with nucleolin via their cytoplasmic tail.
Keren Farin +3 more
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PLoS ONE, 2010 BackgroundNucleolin is one of the major proteins of the nucleolus, but it is also expressed on the cell surface where is serves as a binding protein for variety of ligands implicated in tumorigenesis and angiogenesis.
Ara G Hovanessian +5 more
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Identification of RSV Fusion Protein Interaction Domains on the Virus Receptor, Nucleolin
Viruses, 2021 Nucleolin is an essential cellular receptor to human respiratory syncytial virus (RSV). Pharmacological targeting of the nucleolin RNA binding domain RBD1,2 can inhibit RSV infections in vitro and in vivo; however, the site(s) on RBD1,2 which interact ...
Peter Mastrangelo +7 more
doaj +1 more source
G-Quadruplex Linked DNA Guides Selective Transfection into Nucleolin-Overexpressing Cancer Cells
Pharmaceutics, 2022 Gene therapy is a promising approach for treating tumors. Conventional approaches of DNA delivery depending on non-viral or viral vectors are unsatisfactory due to the concerns of biosafety and cell-targeting efficiency.
Mengxi Xiang +8 more
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Iranian Journal of Allergy, Asthma and Immunology, 2022 Expression and location of nucleolin are often abnormal in malignancies, which may result in the production of autoantibodies. Despite this, the identification of such autoantibodies may be essential for the early diagnosis and prognosis of cancers.
Fatemeh Ezzatifar +4 more
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Redox Report, 2023 Background: Nucleolin is a multifunctional nucleolar protein with RNA-binding properties. Increased nucleolin expression protects cells from H2O2-induced damage, but the mechanism remains unknown.
Cheng Chen +8 more
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JCI Insight, 2023 Glioblastomas are among the deadliest human cancers and are highly vascularized. Angiogenesis is dynamic during brain development, almost quiescent in the adult brain but reactivated in vascular-dependent CNS pathologies, including brain tumors.
Marc Schwab +19 more
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In vivo Study of the Histone Chaperone Activity of Nucleolin by FRAP
Biochemistry Research International, 2011 Nucleolin is a major nucleolar protein involved in various aspects of ribosome biogenesis such as regulation of polymerase I transcription, pre-RNA maturation, and ribosome assembly.
Xavier Gaume +4 more
doaj +1 more source