Results 31 to 40 of about 2,581 (174)
Molecules, 2019 The highly prescribed antidepressant, citalopram, as one of newly emerging pollutants, has been frequently detected in the aquatic environment. Citalopram oxidation was examined during sodium hypochlorite (NaOCl) and chlorine dioxide (ClO2) chlorination ...
Juan Lv, Yan Wang, Na Li
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Heliyon, 2023 N- Nitrosodimethyl amine, the simplest member of the N-Nitrosamine family, is a carcinogenic and mutagenic agent that has gained considerable research interest owing to its toxic nature.
Rehin Sulay +3 more
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NDMA Formation by Chloramination of Ranitidine: Kinetics and Mechanism [PDF]
Environmental Science & Technology, 2012 The kinetics of decomposition of the pharmaceutical ranitidine (a major precursor of NDMA) during chloramination was investigated and some decomposition byproducts were identified by using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS).
Le Roux, Julien +4 more
openaire +4 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Since July 2018, numerous lots of valsartan have been found to be contaminated with N‐nitrosodimethylamine (NDMA). We aimed to assess the association between exposure to valsartan products contaminated with NDMA and the risk of cancer. Methods
Imène Mansouri +4 more
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Involvement of PSMD10, CDK4, and Tumor Suppressors in Development of Intrahepatic Cholangiocarcinoma of Syrian Golden Hamsters Induced by Clonorchis sinensis and N-Nitrosodimethylamine. [PDF]
PLoS Neglected Tropical Diseases, 2015 Clonorchis sinensis is a group-I bio-carcinogen for cholangiocarcinoma (CCA). Although the epidemiological evidence links clonorchiasis and CCA, the underlying molecular mechanism involved in this process is poorly understood.
Md Hafiz Uddin +4 more
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Metabolism Open, 2022 Idiopathic lung fibrosis (ILF) is a severe and life threatening lung disorder that is characterized by scarring of lung tissue, leading to thickening and stiffening of affected areas.
Oluwatobi T. Somade +9 more
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N-Nitrosodimethylamine Contamination in the Metformin Finished Products
Molecules, 2020 A GC–MS/MS method with EI ionization was developed and validated to detect and quantify N-nitrosodimethylamine (NDMA) and seven other nitrosamines in 105 samples of metformin tablets from 13 different manufactures.
Adam Zmysłowski +2 more
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Chemical & pharmaceutical bulletin, 2021 N-Nitrosodimethylamine (NDMA) is a probable human carcinogen. This study investigated the root cause of the presence of NDMA in ranitidine hydrochloride. Forced thermal degradation studies of ranitidine hydrochloride and its inherent impurities (Imps. A, B, C, D, E, F, G, H, I, J, and K) listed in the European and United States Pharmacopeias revealed ...
Yokoo, Hidetomo +8 more
openaire +2 more sources
Applied Sciences, 2021 A novel HPLC method with fluorimetric detection was developed for the determination of potentially carcinogenic N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) in active pharmaceutical ingredient enalapril maleate.
Dariusz Boczar +4 more
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Results in ChemistryN-nitrosodimethylamine (NDMA), a highly potent carcinogen, poses significant pollution concerns in the atmosphere. The experimental methods and density functional theory (DFT) methods are employed herein to unveil the role of O3 and HO·role on the NDMA ...
Dan Huang +6 more
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