Results 101 to 110 of about 599,165 (331)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Placing the Near-Earth Object Impact Probability in Context

open access: yesThe Planetary Science Journal
Near-Earth objects (NEOs) have the potential to cause extensive damage and loss of life on Earth. Advancements in NEO discovery, trajectory prediction, and deflection technology indicate that an impact could be prevented, with sufficient warning time. We
C. R. Nugent   +7 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Sensitivity Testing of Stereophotoclinometry for the OSIRIS-REx Mission. II. Effective Observation Geometry for Digital Terrain Modeling

open access: yesThe Planetary Science Journal
The OSIRIS-REx mission used stereophotoclinometry (SPC) to generate digital terrain models (DTMs) of its target asteroid, Bennu. Here we present a suite of preflight tests conducted to identify the observing geometry and number of images needed to create
Eric E. Palmer   +11 more
doaj   +1 more source

Gravitational capture opportunites for asteroid retrieval missions [PDF]

open access: yes, 2012
Asteroids and comets are of strategic importance for science in an effort to uncover the formation, evolution and composition of the Solar System. Near-Earth objects (NEOs) are of particular interest because of its accessibility from Earth, but also ...
Alessi, Elisa Maria   +3 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Evaluating Short-warning Mitigation via Intentional Robust Disruption of a Hypothetical Impact of Asteroid 2023 NT1

open access: yesThe Astrophysical Journal
We investigate various short-warning mitigation scenarios via fragmentation for a hypothetical impact of asteroid 2023 NT1, a near-Earth object (NEO) that was discovered on 2023 July 15, two days after its closest approach to Earth on July 13.
Brin Bailey   +10 more
doaj   +1 more source

Statistical Analysis of Near Earth Objects [PDF]

open access: yes
In this paper, we explore the statistical properties of Near Earth Objects (NEOs). It is determined whether the date has an effect on the quantity of NEOs observed, as well as if the velocities, sizes and orbit types of the NEO are correlated with the ...
Danielle Bisordi, Kristin Buckley
core  

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