Results 101 to 110 of about 584,066 (367)

Compositional study of asteroids in the Erigone collisional family using visible spectroscopy at the 10.4 m GTC

, 2016
Two primitive near Earth asteroids, (101955) Bennu and (162173) Ryugu, will be visited by a spacecraft with the aim of returning samples back to Earth.
Alí-Lagoa, Víctor, Cabrera-Lavers, Antonio, Campins, Humberto, de León, Julia, De Prá, Mário, Licandro, Javier, Morate, David, Pinilla-Alonso, Noemí   +7 more
core   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Modeling Linear Polarization of the Didymos–Dimorphos System before and after the DART Impact

The Planetary Science Journal
We analyze the polarization observations of the Didymos–Dimorphos system before and after the impact by the NASA Double Asteroid Redirection Test spacecraft on Dimorphos.
Antti Penttilä, Karri Muinonen, Mikael Granvik, Zuri Gray, Stefano Bagnulo, Ludmilla Kolokolova, Fernando Moreno   +6 more
doaj   +1 more source

Earth-approaching asteroids: Populations, origin, and compositional types [PDF]

Origin, physical properties, and discovery history of smaller asteroids are reviewed. They appear to link the main belt objects, namely the comets and meteorites.
Helin, E. F., Shoemaker, E. M.
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Visual-band Brightnesses of Near-Earth Objects that will be Discovered in the Infrared by NEO Surveyor

The Planetary Science Journal
Near-Earth Object (NEO) Surveyor will detect asteroids and comets using mid-infrared thermal emission, however ground-based followup resources will require knowledge of the expected visible light brightness in order to plan characterization observations.
Joseph R. Masiero, Tyler Linder, Amy Mainzer, Dar W. Dahlen, Yuna G. Kwon   +4 more
doaj   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Data‐driven performance metrics for neural network learning

International Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary Effectiveness of data‐driven neural learning in terms of both local mimima trapping and convergence rate is addressed. Such issues are investigated in a case study involving the training of one‐hidden‐layer feedforward neural networks with the extended Kalman filter, which reduces the search for the optimal network parameters to a state ...
Angelo Alessandri, Mauro Gaggero, Marcello Sanguineti   +2 more
wiley   +1 more source

Sensitivity Testing of Stereophotoclinometry for the OSIRIS-REx Mission. II. Effective Observation Geometry for Digital Terrain Modeling

The Planetary Science Journal
The OSIRIS-REx mission used stereophotoclinometry (SPC) to generate digital terrain models (DTMs) of its target asteroid, Bennu. Here we present a suite of preflight tests conducted to identify the observing geometry and number of images needed to create
Eric E. Palmer, John R. Weirich, Robert W. Gaskell, Diane Lambert, Tanner Campbell, Kris Drozd, Olivier S. Barnouin, Michael G. Daly, Kenneth Getzandanner, John N. Kidd Jr., Coralie D. Adam, Dante S. Lauretta   +11 more
doaj   +1 more source