Results 61 to 70 of about 584,066 (367)
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Origin and dynamics of Near Earth Objects
Abstract The population of Near-Earth Objects (NEOs) evolves on orbits which can cross the orbit of the Earth. Most NEOs come from the asteroid belt via unstable zones associated with powerful or diffusive resonances. Their evolutionary paths and the statistical properties of their dynamics have been determined by massive numerical integrations.
Michel, P., Morbidelli, A., Bottke, W.F.
openaire +2 more sources
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Near-Earth Objects (NEO) and other current space threats
Objectives The subject of the study are space threats – Near-Earth Objects (NEO) and Potentially Hazardous Asteroids (PHA). Methods The research methods employed in this article included the classic theoretical methods used in security sciences and a
Radosław Bielawski
doaj +1 more source
WORKING GROUP: NEAR-EARTH OBJECTS [PDF]
Following its meeting in May, 2010, the IAU Executive Committee requested that a Working Group on NEOs within Div. III be re-activated and carry out the following activities: a) investigate and formulate requirements for an international ground- and/or space-based NEO survey, to detect, track and characterize (optical/IR, radar) 90% of all
David Morrison+2 more
openaire +2 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Encounter Circumstances of Asteroid 99942 Apophis with the Catalog of Known Asteroids
Asteroid 99942 Apophis will pass near Earth in 2029 April. Expected to miss our planet by a safe margin, that could change if Apophis's path were perturbed by a collision with another asteroid in the interim.
Paul Wiegert, Benjamin Hyatt
doaj +1 more source
The Second International Asteroid Warning Network Timing Campaign: 2005 LW3
The Earth close approach of near-Earth asteroid 2005 LW3 on 2022 November 23 represented a good opportunity for a second observing campaign to test the timing accuracy of astrometric observation. With 82 participating stations, the International Asteroid
Davide Farnocchia+92 more
doaj +1 more source
NEOWISE Reactivation Mission Year Three: Asteroid Diameters and Albedos [PDF]
The Near-Earth Object Wide-field Infrared Survey Explorer (NEOWISE) reactivation mission has completed its third year of surveying the sky in the thermal infrared for near-Earth asteroids and comets.
Bauer, J. M.+8 more
core +3 more sources
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source