Results 61 to 70 of about 584,066 (367)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Origin and dynamics of Near Earth Objects

open access: yesComptes Rendus. Physique, 2005
Abstract The population of Near-Earth Objects (NEOs) evolves on orbits which can cross the orbit of the Earth. Most NEOs come from the asteroid belt via unstable zones associated with powerful or diffusive resonances. Their evolutionary paths and the statistical properties of their dynamics have been determined by massive numerical integrations.
Michel, P., Morbidelli, A., Bottke, W.F.
openaire   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Near-Earth Objects (NEO) and other current space threats

open access: yesSecurity and Defence Quarterly, 2020
Objectives The subject of the study are space threats – Near-Earth Objects (NEO) and Potentially Hazardous Asteroids (PHA). Methods The research methods employed in this article included the classic theoretical methods used in security sciences and a
Radosław Bielawski
doaj   +1 more source

WORKING GROUP: NEAR-EARTH OBJECTS [PDF]

open access: yesProceedings of the International Astronomical Union, 2011
Following its meeting in May, 2010, the IAU Executive Committee requested that a Working Group on NEOs within Div. III be re-activated and carry out the following activities: a) investigate and formulate requirements for an international ground- and/or space-based NEO survey, to detect, track and characterize (optical/IR, radar) 90% of all
David Morrison   +2 more
openaire   +2 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

Encounter Circumstances of Asteroid 99942 Apophis with the Catalog of Known Asteroids

open access: yesThe Planetary Science Journal
Asteroid 99942 Apophis will pass near Earth in 2029 April. Expected to miss our planet by a safe margin, that could change if Apophis's path were perturbed by a collision with another asteroid in the interim.
Paul Wiegert, Benjamin Hyatt
doaj   +1 more source

The Second International Asteroid Warning Network Timing Campaign: 2005 LW3

open access: yesThe Planetary Science Journal, 2023
The Earth close approach of near-Earth asteroid 2005 LW3 on 2022 November 23 represented a good opportunity for a second observing campaign to test the timing accuracy of astrometric observation. With 82 participating stations, the International Asteroid
Davide Farnocchia   +92 more
doaj   +1 more source

NEOWISE Reactivation Mission Year Three: Asteroid Diameters and Albedos [PDF]

open access: yes, 2017
The Near-Earth Object Wide-field Infrared Survey Explorer (NEOWISE) reactivation mission has completed its third year of surveying the sky in the thermal infrared for near-Earth asteroids and comets.
Bauer, J. M.   +8 more
core   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

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