Results 121 to 130 of about 36,590 (291)

Incremental Dynamic Analysis of Mid-Rise Buildings with Buckling Restrained Brace Frame System under Pulse-Like Near-Fault Ground Motions [PDF]

Journal of Rehabilitation in Civil Engineering
Buckling Restrained Braced Frames (BRBFs) are frequently utilized as seismic force-resisting systems due to their considerable ductility and energy dissipation capacity.
Yaghub Minaei, Mohammadreza Mashayekhi, Mohammad Sarcheshmehpour   +2 more
doaj   +1 more source

Influence of seismic events on shallow geotechnical structures [PDF]

, 2017
This paper deals with a summary of possible seismic loading of shallow geotechnical structures. It is known that seismic loading influences the underground structures much less than the structures on the surface, therefore, it is not usually taken into ...
Kaláb, Zdeněk, Štemon, Pavel
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Near-Fault Response and Loading Protocols of Box Columns in Steel Frames with Self-Centering Braces to Provide Recentering Capability

Advances in Civil Engineering
The main objective of this study was to establish loading protocols for self-centering braced frames (SCBFs) while taking into account the impact of near-fault ground motions.
Yu-Fang Liu, Chung-Che Chou, Chia-Ying Chung, Hao-Che Huang   +3 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Optimal Design and Seismic Performance of Base-Isolated Structures with Varying Heights Equipped with Tuned Inerter Dampers Subjected to Far-Fault and Near-Fault Ground Motions

Applied Sciences
This paper investigates the optimal design of base-isolated structures equipped with tuned inerter dampers (TIDs) subjected to various ground motions. The Clough–Penzien model is employed to simulate the power spectrum of three types of ground motions ...
Yingjie Kang, Zewen Zhang, Zeyu Zhang, Xinyu Zhang, Qingkuan Liu   +4 more
doaj   +1 more source

Analysis of accelerograms—Parkfield earthquake [PDF]

, 1967
Integrated velocities and displacements show that near the fault at Cholame the surface motion exhibited a transient horizontal displacement pulse of approximately ten inches amplitude and one and one-half seconds duration, normal to the fault.
Housner, G. W., Trifunac, M. D.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Postseismic rebound due to creep of the lower lithosphere and asthenosphere [PDF]

Postseismic surface deformations are attributed to the inelastic flow of the subcrustal regions of the Earth following an earthquake. A multilayer representation of the Earth's rheological properties is used in conjunction with a finite element ...
Cohen, S. C.
core   +1 more source