Results 121 to 130 of about 1,827,561 (316)
Effect of a Near Fault on the Seismic Response of a Base-Isolated Structure with a Soft Storey
Slovak Journal of Civil Engineering, 2017 This study focuses on the soft-storey behavior of RC structures with lead core rubber bearing (LRB) isolation systems under near and far-fault motions.
Athamnia B., Ounis A., Abdeddaim M.
doaj +1 more source
Transient response of bridge piers under eccentric impact of near-fault earthquake. [PDF]
Sci Rep, 2022 Wang Z, Zeng Q, Du Y, An W.
europepmc +1 more source
General computational approach for optimal fault detection
, 2009 We propose a new computational approach to solve the optimal fault detection problem in the most general setting. The proposed procedure is free of any technical assumptions and is applicable to both proper and non-proper systems.
Andras Varga, Varga, Andreas
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Influence of source directivity and site effects of 2003 Tokachi-oki earthquake on the generation of high PGA in the near-fault zones. [PDF]
Sci Rep, 2022 Pavlenko OV.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Discrete Element Modeling of Near-Surface Fault Rupture Evolution Along the Milun Fault in Taiwan
Applied SciencesUnderstanding the shallow rupture mechanisms on coseismic faults and assessing the influence of fault area propagation is essential for disaster prevention.
Xiao-Fei Guo, Yosuke Aoki, Jiang-Hai Li
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Terrestrial, Atmospheric and Oceanic Sciences, 2011 Rapid convergence between the Eurasian plate and the Philippine Sea plate in the northern Longitudinal Valley near the city of Hualien in eastern Taiwan has produced prominent fault scarps and large earthquakes (M ¡_ 7).
Jiun-Yee Yen +8 more
doaj +1 more source