Results 51 to 60 of about 319,032 (135)

A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products. [PDF]

PLoS Pathogens, 2018
The properties of the human immunodeficiency virus (HIV) pose serious difficulties for the development of an effective prophylactic vaccine. Here we describe the construction and characterization of recombinant (r), replication-competent forms of rhesus ...
Young C Shin, Georg F Bischof, William A Lauer, Lucas Gonzalez-Nieto, Eva G Rakasz, Gregory M Hendricks, David I Watkins, Mauricio A Martins, Ronald C Desrosiers   +8 more
doaj   +1 more source

Next Generation Sequencing Technologies for Insect Virus Discovery

Viruses, 2011
Insects are commonly infected with multiple viruses including those that cause sublethal, asymptomatic, and latent infections. Traditional methods for virus isolation typically lack the sensitivity required for detection of such viruses that are present ...
Sijun Liu, Diveena Vijayendran, Bryony C. Bonning   +2 more
doaj   +1 more source

Characterization of Intact Proviruses in Blood and Lymph Node from HIV-Infected Individuals Undergoing Analytical Treatment Interruption. [PDF]

, 2019
The role of lymphoid tissue as a potential source of HIV-1 rebound following interruption of antiretroviral therapy (ART) is uncertain. To address this issue, we compared the latent viruses obtained from CD4+ T cells in peripheral blood and lymph nodes ...
Ablanedo-Terrazas, Yuria, Barton, John P, Cohen, Yehuda Z, Damsgaard, Tine, Del Rio Estrada, Perla M, Denton, Paul W, Garcia Noceda, Marco, Lorenzi, Julio CC, Lu, Ching-Lan, Nussenzweig, Michel C, Oliveira, Thiago Y, Pai, Joy A, Reyes-Teran, Gustavo, Søgaard, Ole S, Tolstrup, Martin, Vibholm, Line K   +15 more
core   +1 more source

Characterization of HIV-1 Near Full-Length Proviral Genome Quasispecies from Patients with Undetectable Viral Load Undergoing First-Line HAART Therapy

Viruses, 2017
Increased access to highly active antiretroviral therapy (HAART) by human immunodeficiency virus postive (HIV+) individuals has become a reality worldwide. In Brazil, HAART currently reaches over half of HIV-infected subjects.
Brunna M. Alves, Juliana D. Siqueira, Marianne M. Garrido, Ornella M. Botelho, Isabel M. Prellwitz, Sayonara R. Ribeiro, Esmeralda A. Soares, Marcelo A. Soares   +7 more
doaj   +1 more source

The Metagenomic Analysis of Viral Diversity in Colorado Potato Beetle Public NGS Data

Viruses, 2023
The Colorado potato beetle (CPB) is one of the most serious insect pests due to its high ecological plasticity and ability to rapidly develop resistance to insecticides.
Maria Starchevskaya, Ekaterina Kamanova, Yuri Vyatkin, Tatyana Tregubchak, Tatyana Bauer, Sergei Bodnev, Ulyana Rotskaya, Olga Polenogova, Vadim Kryukov, Denis Antonets   +9 more
doaj   +1 more source

Differential analysis of HIV-1 near full-length genome subtypes and mutations using NGS and TGS technologies

Guangxi Yike Daxue xuebao
Objective To compare next-generation sequencing(NGS) and third-generation sequencing(TGS) technologies in HIV-1 subtype determination, drug resistance mutation detection, and identification of high- and low-frequency variants. Methods A total of 50 newly
Qiao Qiu, Peijiang Pan, Huiqi Pan, Rongfeng Chen, Bingyu Liang, Yanyan Liao, Linyan Tang, Junjun Jiang, Hao Liang, Li Ye   +9 more
doaj   +1 more source

Genomic analysis of 48 paenibacillus larvae bacteriophages [PDF]

, 2018
Indexación: Scopus.Funding: Research at UNLV was funded by National Institute of General Medical Sciences grant GM103440 (NV INBRE), the UNLV School of Life Sciences, and the UNLV College of Sciences. E.C.-N.
Castro-Nallar, E., Fajardo, C.P., Grose, J.H., Hope, S., Mendez, K.N., Stamereilers, C., Tsourkas, P.K., Walker, J.K.   +7 more
core   +1 more source

Sequencing of Kaposi's Sarcoma Herpesvirus (KSHV) genomes from persons of diverse ethnicities and provenances with KSHV-associated diseases demonstrate multiple infections, novel polymorphisms, and low intra-host variance.

PLoS Pathogens
Recently published near full-length KSHV genomes from a Cameroon Kaposi sarcoma case-control study showed strong evidence of viral recombination and mixed infections, but no sequence variations associated with disease.
Vickie A Marshall, Elena M Cornejo Castro, Charles A Goodman, Nazzarena Labo, Isabella Liu, Nicholas C Fisher, Kyle N Moore, Ananthakrishnan Nair, Taina Immonen, Brandon F Keele, Mark N Polizzotto, Thomas S Uldrick, Yunxiang Mu, Tanuja Saswat, Laurie T Krug, Kevin M McBride, Kathryn Lurain, Ramya Ramaswami, Robert Yarchoan, Denise Whitby   +19 more
doaj   +1 more source

Identification of New HIV-1 Circulating Recombinant Forms CRF81_cpx and CRF99_BF1 in Central Western Brazil and of Unique BF1 Recombinant Forms

Frontiers in Microbiology, 2019
Intersubtype recombinants classified as circulating recombinant forms (CRFs) or unique recombinant forms (URFs) have been shown to play an important role in the complex and dynamic Brazilian HIV/AIDS epidemic.
Mônica N. G. Reis, Monick L. Guimarães, Gonzalo Bello, Mariane M. A. Stefani   +3 more
doaj   +1 more source

Large-scale discovery of enhancers from human heart tissue. [PDF]

, 2011
Development and function of the human heart depend on the dynamic control of tissue-specific gene expression by distant-acting transcriptional enhancers.
Afzal, Veena, Akiyama, Jennifer A, Black, Brian L, Blow, Matthew J, Bristow, James, Holt, Amy, Jensen, Brian C, Kaplan, Tommy, May, Dalit, McCulley, David J, Pennacchio, Len A, Plajzer-Frick, Ingrid, Rubin, Edward M, Shoukry, Malak, Simpson, Paul C, Visel, Axel, Wright, Crystal   +16 more
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