Results 81 to 90 of about 807,286 (280)

Preferred clinical practice in convergence insufficiency in India: A survey

Indian Journal of Ophthalmology, 2008
Purpose: Convergence insufficiency (CI) is a common binocular vision disorder. However, there is a lack of consensus regarding the treatment most appropriate for CI.
Patwardhan Sourabh, Sharma Pradeep, Saxena Rohit, Khanduja Sumeet   +3 more
doaj  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Virtual Reality Orthoptic Interventions for Binocular Vision Disorders: A Systematic Review and Meta-Analysis

Journal of Eye Movement Research
Purpose: To systematically review and meta-analyze randomized controlled trials (RCTs) evaluating digital orthoptic interventions, including virtual reality (VR)–based approaches, for convergence insufficiency and intermittent exotropia.
Clara Martinez-Perez, Noelia Nores-Palmas, Jacobo Garcia-Queiruga, Maria J. Giraldez, Eva Yebra-Pimentel   +4 more
doaj   +1 more source

Sequential Data-Adaptive Bandwidth Selection by Cross-Validation for Nonparametric Prediction

, 2010
We consider the problem of bandwidth selection by cross-validation from a sequential point of view in a nonparametric regression model. Having in mind that in applications one often aims at estimation, prediction and change detection simultaneously, we ...
Ansgar Steland, Brodsky B. E., Eubank R. L., Härdle W., Müller H.-G., Pawlak M., Van der Vaart A., Wand M. P.   +7 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Functional activity changes after vergence and accommodative rehabilitation of concussion-related convergence insufficiency: CONCUSS clinical trial fMRI results

Frontiers in Neuroscience
IntroductionThe CONCUSS clinical trial examined the neural changes associated with office-based vergence/accommodative therapy with movement (OBVAM) in concussion-related convergence insufficiency (CONC-CI).MethodsThe following assessments were collected
Ayushi Sangoi, Farzin Hajebrahimi, Suril Gohel, Mitchell Scheiman, Arlene Goodman, Arlene Goodman, Melissa Noble, Tara L. Alvarez   +7 more
doaj   +1 more source

Convergence of the critical attractor of dissipative maps: Log-periodic oscillations, fractality and nonextensivity

, 2000
For a family of logistic-like maps, we investigate the rate of convergence to the critical attractor when an ensemble of initial conditions is uniformly spread over the entire phase space. We found that the phase space volume occupied by the ensemble W(t)
A.N. Kolmogorov, C. Beck, C. Tsallis, C. Tsallis, C. Tsallis, C. Tsallis, C.R. da Silva, D. Sornette, D. Sornette, F. A. B. F. de Moura, M. L. Lyra, M.H. Jensen, M.J. Feigenbaum, M.J. Feigenbaum, M.L. Lyra, M.L. Lyra, P. Coullet, R.C. Ball, R.O. Vallejos, S. Drozdz, T.A. Halsey, U. Tirnakli, U. Tirnakli, U.M.S. Costa, W.I. Newman, Ya. Pesin, Ya.G. Sinai   +26 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source