Results 81 to 90 of about 102,036 (238)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effectiveness of binocular vision therapy in managing patients with intermittent exotropia

Indian Journal of Ophthalmology
Purpose: Evaluating the effect of binocular vision training (BVT) on Newcastle Control Score (NCS)-Home, near stereopsis and convergence amplitudes in intermittent exotropia (IXT). Design: Retrospective observational study. Methods: 30 subjects diagnosed
Affan Ashfaque Ahmed Ansari, Pradeep Sharma, Erum W Khateeb, Faiza Bhombal, Shruti Lad, Varsha Jain, Areeba Usmani, Antariksh Jain, Md Oliullah Abdal   +8 more
doaj   +1 more source

Semi-analytical approximation of the normal derivative of the heat simple layer potential near the boundary of a two-dimensional domain [PDF]

Известия Саратовского университета. Новая серия: Математика. Механика. Информатика
A semi-analytical approximation of the normal derivative of the simple layer heat potential near the boundary of a two-dimensional domain with $C^{5} $ smoothness is proposed.
Ivanov, Dmitrii Yurievich
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The association of carotid cavernous fistula with Graves′ ophthalmopathy

Indian Journal of Ophthalmology, 2013
Graves′ ophthalmopathy (GO) is one of the frequent manifestations of the disorder which is an inflammatory process due to fibroblast infiltration, fibroblast proliferation and accumulation of glycosaminoglycans. Eye irritation, dryness, excessive tearing,
Ozlem Celik, Deram Buyuktas, Civan Islak, A Murat Sarici, A Sadi Gundogdu   +4 more
doaj   +1 more source

Agreement between three methods for measuring near point of convergence among patients with different refractive errors. [PDF]

Saudi J Ophthalmol, 2021
Baskaran AA, Britto T, Sowndher RT, Thomas PA.   +3 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The distribution of the near point of convergence and its related factors in an elderly population: the Tehran Geriatric Eye Study (TGES). [PDF]

Eye (Lond), 2021
Hashemi H, Nabovati P, Jamali A, Pakbin M, Yekta A, Aghamirsalim M, Asadollahi M, Khabazkhoob M.   +7 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source