Results 111 to 120 of about 7,318 (296)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
, 2016 Straight spaces are spaces for which a continuous map defined on the space which is uniformly continuous on each set of a finite closed cover is then uniformly continuous on the whole space. Previously, straight spaces have been studied in the setting of
Bentley, H.L., Ori, R.G.
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Apartness, compactness and nearness
, 2008 We investigate constructively a pre-apartness structure that is classically important in the characterisation of compact proximity spaces, and that may help identify a good constructive notion of compactness for not-necessarily-uniform apartness spaces ...
Ishihara, Hajime +3 more
core +1 more source
The Study of Ayatollah Mesbah Yazdi’s Philosophical Theory in Comparison with the Issue of “Unity” [PDF]
اخلاق وحیانی, 2014 The theory of ayatollah Mesbah must be presented through the two issues of “the analysis of ethical deeds” and “the analysis of ethical statements”. With regard to the first issue, ayatollah Mesbah believes that the main and axial drive in human beings ...
Ali Mohammadi, Yahya Abdullahi
doaj
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Nearness Relations in Environmental Space
, 2001 This paper presents an experiment with human subjects concerning the vague spatial relation ‘near ’ in environmental space. After the topic is introduced and relevant previous work surveyed, the experiment is described.
Michael F Worboys
core
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
A note on almost uniform nearness frames
, 2011 We show that the category of almost uniform nearness frames is co-reflective in the category of all nearness frames with interpolative uniformly below relation. This we do by actually constructing the coreflection. The resulting functor commutes with the
Mugochi, Martin M, Dube, Themba
core