Results 111 to 120 of about 8,970 (252)
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
On the Strict Completion of a Nearness Space
, 2004 The strict completion of a nearness space was constructed in 1974 in Herrlich's original paper on nearness. we present an external characterization of this completion. Among the consequences of this result is the fact that for nearness spaces X and
Bentley, HL, Herrlich, H
core
Nearness Relations in Environmental Space
, 2001 This paper presents an experiment with human subjects concerning the vague spatial relation ‘near ’ in environmental space. After the topic is introduced and relevant previous work surveyed, the experiment is described.
Michael F Worboys, Michael F. Worboys
core +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Scientific ReportsTo evaluate the recurrence rate and risk factors of recurrence after robot-assisted laparoscopic partial nephrectomy for solitary renal cell carcinoma (RCC). A total of 1265 cases of initial solitary localized RCC were analyzed.
Jae Hoon Chung +8 more
doaj +1 more source
Bounded proximities and related nearness
, 2013 The new created concept Bounded Topology, a convenient foundation for topology, (see [9]) deals with a lot kind of structures examined by topologists in the past: Especially, generalized convergence spaces, now de ned as b-convergences in [8], appear in ...
Leseberg, Dieter
core
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
On the epireflective hull of topological nearness groups in the category of nearness groups
, 2007 To find the specific nature of the objects that are in the epireflective hull of the symmetric topological spaces in the category of nearness spaces is a long open problem. See [BCH05]for more information.
Gompa, Vijaya L, Bentley, H Lamar
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source