Results 101 to 110 of about 8,970 (252)
On the Campanato nearness condition
, 1994 We prove a Lax-Milgram type theorem using the concept of nearness between ...
Leonardi, Salvatore
core
Connection Properties in Nearness Spaces
, 1985 We prove that a topological space X has a locally connected regular T1, extension if and only if X is the underlying topological space of a nearness space Y which is concrete, regular and uniformly locally uniformly connected.
H. L. Bentley, R. G. Ori, D. Baboolal
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Locally finite nearness frames. [PDF]
, 1998 Thesis (M.Sc.)-University of Durban-Westvile, 1998.The concept of a frame was introduced in the mid-sixties by Dowker and Papert. Since then frames have been extensively studied by several authors, including Banaschewski, Pultr and Baboolal to mention ...
Naidoo, Inderasan.
core +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The Study of Ayatollah Mesbah Yazdi’s Philosophical Theory in Comparison with the Issue of “Unity” [PDF]
اخلاق وحیانی, 2014 The theory of ayatollah Mesbah must be presented through the two issues of “the analysis of ethical deeds” and “the analysis of ethical statements”. With regard to the first issue, ayatollah Mesbah believes that the main and axial drive in human beings ...
Ali Mohammadi, Yahya Abdullahi
doaj
The Tamano-Dowker type theorems for nearness frames
, 1995 Through the coproduct of two nearness frames we prove the localic version of the Tamano-Dowker type theorems for nearness spaces as obtained by Bentley (1991).
Dube, T.A.
core +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source