Results 91 to 100 of about 8,970 (252)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ordered gamma nearness semigroups
Near set theory, which is a generalization of rough set theory, is based on the determination of universal sets according to the available information of the objects. In this paper, we state the way of defining ordered Gamma\documentclass[12pt]{minimal} \
Ozturk, Mehmet Ali, Tekin, Ozlem
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
L-Fuzzy rough point-wise proximity spaces
Applied General TopologyIn this paper, we study the concept of nearness between L-fuzzy rough sets and L-fuzzy points. The nearness between two L-fuzzy rough sets are viewed in terms of this new concept.
Virendra Kumar, Surabhi Tiwari
doaj +1 more source
The Pitman nearness criterion and its determination
, 1986 A general method for determining Pitman Nearness is given In the case of univariate estimators. This method is then applied to some estimation problems. The concept of Pitman Nearness is also generalized to the multivariate case.
Rao, C. R. +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Jixie chuandong, 1994 In this paper, the concepts about similarity factor and nearness are summarized and a new method of pattern distinguished based on the fuzzy similarity nearness （PFSN） is proposed.
余成波, 梁德沛
doaj
?-RINGS OF WEAK COSETS IN NEARNESS APPROXIMATION SPACES
, 2021 This article introduces Gamma-ring of all near weak cosets in nearness approximation spaces via new operations on the set of all near weak cosets.
Inan, Ebubekir, Uckun, Mustafa
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source