Results 71 to 80 of about 51,287 (284)
Celebrating Professor Themba A. Dube (A TAD Celebration I) [PDF]
This is the first in a series of survey papers featuring the mathematical contributions of Themba Dube to pointfree topology and ordered algebraic structures.
Inderasan Naidoo
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
This paper is a study of implementation of emotional branding in library services. Emotional branding is a new paradigm in marketing world. It means create emotional nuance and its objective is to create an emotional nearness between a brand and its ...
Neneng Komariah +2 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Generalized Grey Target Decision Method for Mixed Attributes Based on Connection Number
Grey target decision model for mixed attributes including real numbers, interval numbers, triangular fuzzy numbers, and trapezoidal fuzzy numbers is complex for its data processing in different ways and information distortion in handling fuzzy numbers ...
Jinshan Ma, Changsheng Ji
doaj +1 more source
Bayesian matching of unlabelled point sets using Procrustes and configuration models [PDF]
The problem of matching unlabelled point sets using Bayesian inference is considered. Two recently proposed models for the likelihood are compared, based on the Procrustes size-and-shape and the full configuration.
Dryden, Ian L., Kenobi, Kim
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
In this paper we develop some combinatorial models for continuous spaces. In this spirit we study the approximations of continuous spaces by graphs, molecular spaces and coordinate matrices. We define the dimension on a discrete space by means of axioms,
A. Rosenfeld +19 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

