Results 131 to 140 of about 231,445 (248)

Mitophagy and Bip–PERK–eIF2α–ATF4 Axis‐Mediated ER Stress Mediate Miriplatin‐Loaded Liposome's Anti‐Colorectal Cancer Action

Cell Proliferation, EarlyView.
LMPt enters the cell mainly through caveolin‐mediated endocytosis, and then fuses with endosomes and lysosomes to deliver MPt to mitochondria and the endoplasmic reticulum to induce mitophagy based on the fusion of lysosomes and mitochondria, and endoplasmic reticulum stress and subsequent apoptosis via the Bip–PERK–eIF2α–ATF4 axis to exert an anti ...
Cong Zhao, Yuhan Qiu, Xiaowei Wang, Mengyan Wang, Li Liu, Xiaojun Zhao, Zixiang Gao, Rongguang Shao, Guimin Xia, Wuli Zhao   +9 more
wiley   +1 more source

Bimekizumab efficacy and safety in Chinese patients with psoriasis in the BE SHINING Phase 3 study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In Chinese patients with moderate to severe plaque psoriasis, bimekizumab treatment was well tolerated and led to significantly higher clinical response rates versus placebo, including complete skin clearance. These findings were consistent with global studies and suggest that bimekizumab is an effective treatment option for Chinese people living with ...
Lin Cai, Xiao‐Yong Man, Jinyan Wang, Aihua Wei, Ying Chen, Delphine Deherder, Jun Gao, Bengt Hoepken, Weiwei Sun, Tingting Lei, Jianzhong Zhang, the BE SHINING Study Group   +11 more
wiley   +1 more source

Mutual fund director compensation

Journal of Financial Research, EarlyView.
Abstract We examine director compensation using a large sample of hand‐compiled U.S. mutual fund data. We find that director compensation is positively correlated with observable productive characteristics—workload, experience, and demographics—that capture the benefits from the directors’ monitoring effort.
John Adams, Sattar Mansi, Takeshi Nishikawa   +2 more
wiley   +1 more source

Estimating National and Foreign Trade Elasticities Using Generalized Transport Costs

Journal of Regional Science, Volume 65, Issue 2, Page 471-496, March 2025.
ABSTRACT We introduce the definition of two distinct trade elasticities corresponding to imports from regions located in the same country (national elasticities) and foreign regions located in other countries (foreign elasticities). We resort to a three‐tier nested CES utility structure to derive the corresponding demand gravity equations.
José L. Zofío, Jorge Díaz‐Lanchas, Damiaan Persyn, Javier Barbero   +3 more
wiley   +1 more source

A Retrospective Study of High‐Risk Infants: Insights From a Regional Hospital in Victoria, Australia

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim To determine the magnitude of high‐risk infants cared for at a regional hospital in Victoria, Australia and to identify the resources required to care for them. Methods A retrospective study was conducted between January 2017 and December 2019 in a regional hospital in Victoria, Australia.
Romanie Rodrigo, Reji Thomas, Jennifer You, Shizar Nahidi, Sheikh Arif Maqbool Kozgar   +4 more
wiley   +1 more source

Design of a collimator for breast-specific gamma imaging and assessment of NEC rate for a pet scanner using Monte Carlo simulations and response surface methodology

, 2020
This thesis is composed of two studies that demonstrate the implementation of Monte Carlo (MC) simulations and response surface methodology (RSM) to specific problems in planar and tomographic nuclear medicine imaging.In the first study, the collimator of a planar small field-of-view continuous crystal breast specific gamma camera is optimized by ...
openaire   +1 more source

RE: Comments on cIMPACT‐NOW Update 11

Brain Pathology, EarlyView.
Henning Leske, Richard Doughty, Pitt Niehusmann   +2 more
wiley   +1 more source

‘Why Did You Go to Buda?’: The Humanist Sodality and Mantuan’s Rustic Idyll in Bohuslaus of Hassenstein’s Ecloga sive Idyllion Budae (1503)☆

Renaissance Studies, EarlyView.
Abstract In the late fifteenth century, the Hungarian royal court at Buda was home to a cosmopolitan community of humanists. In early modern historiography, this cultural milieu has often been interpreted as one of the new, emergent ‘centres’ of the Renaissance in East Central Europe.
Eva Plesnik
wiley   +1 more source

‘Who is the Gael who Would Not Weep?’: The Book of the O’Conor Don, Fearghal Óg Mac an Bhaird, and Late Bardic Poetry of Exile

Renaissance Studies, EarlyView.
Abstract This article examines how late bardic poetry transforms the condition of exile into a literary mode that reimagines community and tradition. I argue that poetry of lament, blessing and devotion articulates a broader literary consciousness that anticipates modern notions of a national consciousness. The compilation of bardic verse in manuscript
Daniel T. McClurkin
wiley   +1 more source

Development and production of allogeneic cord blood‐derived red blood cell concentrates for transfusion to extremely preterm neonates, the All‐Cord study

Transfusion, EarlyView.
Abstract Background Extremely preterm neonates often require red blood cell (RBC) transfusions derived from adult donors. These transfusions introduce adult hemoglobin into a neonatal hematopoietic system dominated by fetal hemoglobin (HbF), shifting the oxygen‐dissociation curve and increasing oxygen delivery to immature tissues.
Jip H. van Daelen, Joyce Bestebroer, Herbert Korsten, Christie Vermeulen, Irwin K. M. Reiss, Enrico Lopriore, Pauline M. Snijder, Elise J. Huisman, Thomas R. L. Klei   +8 more
wiley   +1 more source