Results 141 to 150 of about 36,393 (292)

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for ependymomas

Brain Pathology, EarlyView.
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Laveniya Satgunaseelan, Michael E. Buckland, Geeta Chacko, Kenta Masui, Junji Shibahara, Vani Santosh, Maysa Al‐Hussaini, Sung‐Hye Park, Tarik Tihan, Ho‐Keung Ng, Pieter Wesseling, David N. Louis, Chitra Sarkar, Takashi Komori   +13 more
wiley   +1 more source

Demonstrating through-life and NEC requirements for defence systems [PDF]

, 2009
There are two major transformations currently occurring that significantly impact acquisition and management of military systems. Network Enabled Capability (NEC) demands careful consideration of interoperability for delivered systems; new systems must ...
Michael Henshaw (7154948), Esmond N. Urwin (7204817)   +1 more
core  

Afatinib Versus Osimertinib for Non‐Small Cell Lung Cancer With Uncommon EGFR Mutations: Real‐World Outcomes

Cancer Science, EarlyView.
Afatinib and osimertinib showed broadly comparable survival outcomes as first‐line therapy for NSCLC with uncommon EGFR mutations. Treatment may be individualized by mutation subtype, while adding immune checkpoint inhibition to platinum doublet after EGFR‐TKI showed no clear benefit.
Yutaro Nagano, Hiroshi Yokouchi, Ryota Saito, Osamu Honjo, Toshiyuki Sumi, Takayuki Kaburagi, Kenichiro Ito, Yasuyuki Ikezawa, Keiki Yokoo, Hajime Kikuchi, Sayaka Kudo, Masami Yamazoe, Ryota Shigaki, Keita Tagami, Toshiyuki Tenma, Tatsuru Ishikawa, Mamoru Takahashi, Takaaki Sasaki, Hajime Asahina, Shiro Hinotsu, Hirofumi Chiba, Satoshi Oizumi   +21 more
wiley   +1 more source

Seeking evidence for the role of ontological assumptions in the thinking of managers and professionals [PDF]

Shingo's (1988) seminal innovation in the theory of production management can be seen as a re-conceptualization of production as flow rather than transformation (Koskela 1992).
Koskela, Lauri, Rooke, John
core  

Agile NEC research and development, a spiral approach [PDF]

, 2008
How can you stay in control when your short term needs swamp your long term interests? Increasingly, the Dutch Defence has to balance contradicting needs.
Kluiters, C.E., Braakhuis, J.G., Tempelman, F.   +2 more
core  

Hypericin Suppresses Liver Cancer Through Autophagic Degradation of AKT and Eliciting Antitumor Immune Response

Cancer Science, EarlyView.
Hypericin induces autophagic AKT degradation by promoting AKT‐HSPA5 interaction in an S473 phosphorylation‐dependent manner, suppressing HCC growth. It enhances CD8+ T cell‐mediated antitumor immunity and synergizes with anti‐PD‐L1 therapy, showing favorable safety for HCC treatment. ABSTRACT Hepatocellular carcinoma (HCC) is the most prevalent primary
Sien Ma, Qianqian Xu, Mengjuan Zhu, Xianming Ge, Jian Xu, Yan Pan, Mengli Wang, Yuting Zhu, Aoxuan Xu, Hanmeng Liu, GuangHai Xiang, Weipeng Gong, Bao Zhao   +12 more
wiley   +1 more source

Design of a collimator for breast-specific gamma imaging and assessment of NEC rate for a pet scanner using Monte Carlo simulations and response surface methodology

, 2020
This thesis is composed of two studies that demonstrate the implementation of Monte Carlo (MC) simulations and response surface methodology (RSM) to specific problems in planar and tomographic nuclear medicine imaging.In the first study, the collimator of a planar small field-of-view continuous crystal breast specific gamma camera is optimized by ...
openaire   +1 more source

Genomic Evolution and Immune Contexture With Therapeutic Relevance in Pancreatic Neuroendocrine Neoplasms

Cancer Science, EarlyView.
Lineage‐dependent immunogenomic landscapes and biologically informed therapy in pancreatic neuroendocrine neoplasms. Pancreatic neuroendocrine neoplasms display lineage‐dependent immunogenomic landscapes, in which genomic alterations, epigenetic states, antigen‐presentation status, immune‐cell infiltration, and suppressive microenvironments co‐evolve ...
Yohei Tabe, Eito Nakagawa, Daisuke Asano, Eriko Katsuta, Daisuke Ban, Shogo Kumagai   +5 more
wiley   +1 more source

Análisis comparativo del diseño estructural de un edificio de gran altura de acero estructural utilizando la NEC-SE, 2015, y la propuesta de actualización de la NEC-SE, 2024 [PDF]

El estudio realizado presenta un análisis comparativo de un edificio de acero estructural de gran altura, empleando como referencia la Norma Ecuatoriana de la Construcción (NEC), en el capítulo de Peligro Sísmico y Diseño Sismorresistente con base a la ...
Vargas Vásquez, Anderson German, Briceño Alvarez, Dennise Gabriela   +1 more
core  

Tier 2 adult weight management services in the UK: A case study evaluation of local authority provision of targeted services for higher‐risk groups in England

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary In 2021, the UK Government announced additional funding in England for Adult Weight Management Services (AWMS); it was specified that the extra funding must be used to commission or extend existing tier 2 services. The Office for Health Improvement and Disparities encouraged commissioners to prioritise services for higher‐risk groups such as ...
Lorraine McSweeney, Charlotte Rothwell, Ashley Adamson, Simon Barrett, Claire Mathews, Scott Lloyd, Mackenzie Fong   +6 more
wiley   +1 more source