Results 41 to 50 of about 1,016,672 (340)

Flow correlated percolation during vascular network formation in tumors [PDF]

open access: yesPhys. Rev. Lett. 96, 058104 (2006), 2005
A theoretical model based on the molecular interactions between a growing tumor and a dynamically evolving blood vessel network describes the transformation of the regular vasculature in normal tissues into a highly inhomogeneous tumor specific capillary network.
arxiv   +1 more source

ON NECROSIS. [PDF]

open access: yesThe Lancet
n ...
openaire   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Scoring Root Necrosis in Cassava Using Semantic Segmentation [PDF]

open access: yesarXiv, 2020
Cassava a major food crop in many parts of Africa, has majorly been affected by Cassava Brown Streak Disease (CBSD). The disease affects tuberous roots and presents symptoms that include a yellow/brown, dry, corky necrosis within the starch-bearing tissues.
arxiv  

Necrosis and Infection

open access: yes, 2014
Skin infection leading to cutaneous necrosis is a rare condition. The presence of an immunosuppressant state or an impaired vascular network is a risk factor associated with infection spreading and skin necrosis.
Benhadou, Farida, Del Marmol, Véronique
openaire   +2 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Mechanisms and therapeutic targets of ischemic acute kidney injury

open access: yesKidney Research and Clinical Practice, 2019
Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem without effective therapy and is a significant and frequent cause of morbidity and mortality during the perioperative period.
Sang Jun Han, H. Thomas Lee
doaj   +1 more source

EFFECT OF NIFEDIPINE ON APOPTOSIS, NECROSIS AND VIABILITY OF GERMINAL EPITHELIAL CELLS IN THE CONTRALATERAL TESTICLE AND PLASMA TESTOSTERONE LEVELS IN MALE WHITE RATS (RATTUS NORVEGICUS, WISTAR STRAIN) AFTER UNILATERAL TESTICULAR TORSION

open access: yesJurnal Urologi Indonesia, 2019
Objective: To compare the number of apoptosis, necrosis and viability of germinal epithelial cells in the contralateral testicle (CT) and plasma testosterone (PT) levels in white male rats which administered Nifedipine after unilateral testicular torsion 
Hajid Rahmadianto Mardihusodo   +2 more
doaj   +1 more source

Integrated probability of coronary heart disease subject to the -308 tumor necrosis factor-alpha SNP: a Bayesian meta-analysis [PDF]

open access: yes, 2015
We present a meta-analysis of independent studies on the potential implication in the occurrence of coronary heart disease (CHD) of the single-nucleotide polymorphism (SNP) at the -308 position of the tumor necrosis factor alpha (TNF-alpha) gene. We use Bayesian analysis to integrate independent data sets and to infer statistically robust measurements ...
arxiv   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

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