Results 71 to 80 of about 1,549,386 (358)
Linfadenitis tuberculosa en infección VIH: Hallazgos histológicos
Anales de la Facultad de Medicina, 2006 Introducción: La coinfección de virus de inmundeficiencia humana (VIH) y tuberculosis altera la presentación histológica de la tuberculosis; esto es particularmente frecuente en la linfadenitis tuberculosa.
Fernando Arévalo, José Cabanillas
doaj
mBio, 2018 Life-threatening systemic infections often occur due to the translocation of pathogens across the gut barrier and into the bloodstream. While the microbial and host mechanisms permitting bacterial gut translocation are well characterized, these ...
Stefanie Allert +16 more
doaj +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
The independence of and associations among apoptosis, autophagy, and necrosis
Signal Transduction and Targeted Therapy, 2018 Cell death is an essential biological process for physiological growth and development. Three classical forms of cell death—apoptosis, autophagy, and necrosis—display distinct morphological features by activating specific signaling pathways.
Qi Chen, Jian Kang, Caiyun Fu
semanticscholar +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Molecular Oncology, EarlyView.Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza +5 more
wiley +1 more source
Investigation of tumor tissue alteration after experimental chemotherapy [PDF]
Морфологія, 2009 The aim of the present work was the study of tumor tissue alteration after new antineoplastic substance administration in comparison with widely investigated 5-fluorouracil.
Grygorieva E. V.
doaj
Alʹmanah Kliničeskoj Mediciny, 2017 Background: In recent years, the method of photodynamic therapy (PDT) has been increasingly used in clinical oncology. Three non-toxic components play a key role in realization of the anti- tumor effect of PDT: a photosensitizer (PS), local irradiation ...
V. V. Yuzhakov +13 more
doaj +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source