Results 71 to 80 of about 3,363 (137)

Clinicopathologic Characterization of Muscle Biopsy Findings in Overlap Myositis: A Single Tertiary Care Center Experience

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Objective This study aims to describe the muscle biopsy features of overlap myositis (OM) and compare them with other inflammatory myopathies. We analyzed clinical, serological findings, and histopathological patterns in muscle biopsies to understand the features of OM.
Sidra Fatima   +5 more
wiley   +1 more source

Factors associated with refractory autoimmune necrotizing myopathy with anti-signal recognition particle antibodies

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (ANM-SRP) is regarded as refractory myositis, whereby some patients respond poorly to conventional immunosuppression and require B cell depletion treatment.
Yawen Zhao   +4 more
doaj   +1 more source

Two Cases of Statin-Induced Immune-Mediated Necrotizing Myopathy: A Rare Side Effect of Statins

open access: yesRheumato
Statins are effective drugs for lowering cholesterol and reducing cardiovascular risk. Rarely, they can trigger autoimmune myopathies like immune-mediated necrotizing myopathy (IMNM), associated with anti-HMGCR antibodies.
Luis Angel Montero Furelos   +2 more
doaj   +1 more source

Statin Autoimmune Necrotizing Myopathy Diagnosed After a Motor Vehicle Accident

open access: yesMarshall Journal of Medicine, 2019
One of the most commonly prescribed lipid lowering medications are statins. In most cases, statins are well tolerated. In rare instances, statin induced necrotizing autoimmune myositis (SINAM) can occur.
Julia Poe   +2 more
doaj   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

open access: yesMedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 547-561, March 2026.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan   +22 more
wiley   +1 more source

History of diagnosis on idiopathic inflammatory myopathy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2016
The idiopathic inflammatory myopathy (IIM) is a group of clinically heterogeneous, autoimmune-mediated disorders characterized by inflammation of muscle, elevated creatine kinase (CK), interstitial lung disease and other organ systems involvement ...
Wei ZHANG
doaj  

A 64-Year-Old Woman with Chest Pain, Limb Weakness, and Endometrial Cancer

open access: yesCase Reports in Rheumatology, 2017
Necrotizing autoimmune myopathy (NAM) is a rare subgroup of idiopathic inflammatory myopathies (IIM). This pathology usually affects proximal limb muscles and in some cases the myocardium. Patients usually display proximal limb weakness.
Simon Ponthus   +4 more
doaj   +1 more source

Statin-induced autoimmune necrotizing myositis

open access: yesRheumatology, 2016
Myositides comprise a large group of disorders involving limb muscle weakness. In differential diagnosis we have to consider idiopathic myositides, myositides associated with other diseases, and those induced by external factors, e.g.
Katarzyna Ząber   +2 more
doaj   +1 more source

A Case of Statin-Associated Autoimmune Myopathy

open access: yesClinical Medicine Insights: Case Reports, 2017
A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Alexander J Sweidan   +6 more
doaj   +1 more source

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