Results 71 to 80 of about 98,941 (239)

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source

Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis

Microbiome, 2017
BackgroundNecrotizing enterocolitis (NEC) is a catastrophic disease of preterm infants, and microbial dysbiosis has been implicated in its pathogenesis.
M. Pammi, J. Cope, P. Tarr, B. Warner, A. Morrow, V. Mai, K. Gregory, J. S. Kroll, Valerie McMurtry, M. Ferris, L. Engstrand, H. Lilja, E. Hollister, J. Versalovic, J. Neu   +14 more
semanticscholar   +1 more source

Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

Nature Communications, 2020
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants with high mortality rate, indicating the need for precision treatment.
Y. Koike, Bo Li, N. Ganji, Haitao Zhu, H. Miyake, Yong Chen, Carol Lee, Maarten Janssen Lok, C. Zozaya, Ethan Lau, Dorothy Lee, S. Chusilp, Zhen Zhang, M. Yamoto, R. Wu, M. Inoue, K. Uchida, M. Kusunoki, P. Delgado-Olguín, L. Mertens, A. Daneman, S. Eaton, P. Sherman, A. Pierro   +23 more
semanticscholar   +1 more source

Sildenafil for the treatment of necrotizing enterocolitis: an experimental study

Türk Biyokimya Dergisi, 2022
This study was conducted to evaluate whether sildenafil effectively treats necrotizing enterocolitis (NEC).
İpek Sevcan, Güneş Hatice, Yurttutan Sadık, Tolun Fatma, Kazancı Ülkü, Kuloğlu Tuncay, Gullu Ufuk, Güngör Şükrü   +7 more
doaj   +1 more source

Renal function impairment in children with intestinal failure receiving parenteral nutrition: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with intestinal failure are at risk for kidney dysfunction; however, the contributing factors are not well established. We aimed to describe risk factors associated with glomerular and tubular renal dysfunction in children with intestinal failure.
Amanda M. Braga da Mata, Heitor Pons Leite, Eduardo F. Hatanaka, Mariana Janiques Barcia Magalhães Fonseca, Marta Liliane de Almeida Maia, Giovana S. G. Sabio, Maria Fernanda C. de Camargo, Paulo C. Koch Nogueira   +7 more
wiley   +1 more source

Necrotizing enterocolitis is preceded by increased gut bacterial replication, Klebsiella, and fimbriae-encoding bacteria

Science Advances, 2019
Metagenomic analysis identifies microbial signatures preceding necrotizing enterocolitis development in premature infants. Necrotizing enterocolitis (NEC) is a devastating intestinal disease that occurs primarily in premature infants. We performed genome-
M. Olm, Nicholas Bhattacharya, A. Crits-Christoph, B. Firek, Robyn Baker, Yun S. Song, Michael J. Morowitz, J. Banfield   +7 more
semanticscholar   +1 more source

Body composition at 2 years of age in moderate and late preterm infants

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Moderate and late preterm infants (MLPTI, gestational age 32 0/7–36 6/7 weeks) have altered body composition compared to term‐born infants, but data beyond infancy are lacking. This study aimed to assess body composition at 2 years corrected age for prematurity (CA) in MLPTI, compare it to the literature on term‐born infants, and ...
Anne H. Lafeber, Mark Bosch, Dewi van Harskamp, Nicole R. van Veenendaal, Cornelieke S. H. Aarnoudse‐Moens, Johannes B. van Goudoever, Femke de Groof   +6 more
wiley   +1 more source

Recent advances in understanding necrotizing enterocolitis

F1000Research, 2019
Necrotizing enterocolitis is a devastating intestinal disease affecting preterm infants. In spite of ongoing research and advancement in neonatal care, mortality remains high, especially in infants with advanced disease.
Mashriq Alganabi, Carol Lee, E. Bindi, Bo Li, A. Pierro   +4 more
semanticscholar   +1 more source

Gut bacteria are rarely shared by co-hospitalized premature infants, regardless of necrotizing enterocolitis development

eLife, 2015
Premature infants are highly vulnerable to aberrant gastrointestinal tract colonization, a process that may lead to diseases like necrotizing enterocolitis. Thus, spread of potential pathogens among hospitalized infants is of great concern.
Tali Raveh-Sadka, Brian C Thomas, Andrea Singh, Brian Firek, Brandon Brooks, Cindy J Castelle, Itai Sharon, Robyn Baker, Misty Good, Michael J Morowitz, Jillian F Banfield   +10 more
doaj   +1 more source

Osmolality of fortified human milk with contemporary human milk fortifiers

Nutrition in Clinical Practice, EarlyView.
Abstract Background Human milk fortification is critical to support preterm infant growth. Human milk fortifed to caloric densities above manufacturers’ recommendations are often necessary to achieve adequate growth. Fortified milk may be prepared 12–24 h before feeding, although practice variations exist.
Abigail Gardiner, Irmalís Flores González, Carrie Smith, Jacqueline Wessel, Jae H. Kim, Ting Ting Fu   +5 more
wiley   +1 more source