Results 81 to 90 of about 1,004,467 (295)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Dual-processing altruism [PDF]

, 2013
Altruism refers to an other-benefiting behavior that is costly but bears no direct profit to oneself. At least three different forms can be distinguished: help giving, altruistic punishment, and moral courage.
Pirita Kinnunen, Suna, Windmann, Sabine
core   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

The Resilience of Computationalism [PDF]

, 2010
Computationalism—the view that cognition is computation—has always been controversial. It faces two types of objection. According to insufficiency objections, computation is insufficient for some cognitive phenomenon X.
Piccinini, Dr. Gualtiero
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Allport's prejudiced personality today: need for closure as the motivated cognitive basis of prejudice [PDF]

, 2011
In the long history of psychological research on prejudice, Allport's (1954) book The Nature of Prejudice is undoubtedly the foundational work, advancing ideas that remain highly influential and relevant to this day.
Roets, Arne, Van Hiel, Alain
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The implicit relational assessment procedure: emerging reliability and validity data [PDF]

, 2013
The Implicit Relational Assessment Procedure (IRAP) is a measure of ‘implicit cognition' developed on the basis of a contemporary behavioural analysis of language and cognition.
Barnes-Holmes, Barnes-Holmes, Barnes-Holmes, Barnes-Holmes, Barnes-Holmes, Barnes-Holmes, Bortoloti, Bosson, Carpenter, Chan, Chiou, Cullen, Cunningham, Dawson, De Houwer, Fazio, Ferguson, Ferguson, Field, Gawronski, Gray, Greenwald, Greenwald, Greenwald, Greenwald, Greenwald, Hayes, Haynes, Hooper, Hughes, Hughes, Hughes, Hussey, Juarascio, Kelly, Kim, Lane, LeBel, McKenna, Nicholson, Nicholson, Nosek, Nosek, Nunnally, Olson, O’Toole, Parling, Power, Roddy, Roddy, Scheel, Schmukle, Sireci, Stockwell, Timko, Vahey, Vahey   +56 more
core   +1 more source

Pre-service Teachers’ Need for Cognition

Procedia - Social and Behavioral Sciences, 2012
AbstractThe purpose of this study is to investigate the level of pre-service teachers’ need for cognition and to determine how it differs with respect to some variables. A total of 344 pre-service teachers (114 males and 230 females) from 4 different universities participated in this study.
Garipagaoglu, Cagla, Kilic, Hulya, Coskun, Yelkin Diker   +2 more
openaire   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source