Results 201 to 210 of about 20,721 (236)

Combining bioinformatics and machine learning to analyze and validate sepsis-related cell senescence genes and potential drugs. [PDF]

Ren Fail
Pei S, Li D, Yu X, Huang X, Liu J, Song Y, Zhu L, Cui J, Cui Y, Xie K.   +9 more
europepmc   +1 more source

A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research

Animal Models and Experimental Medicine, EarlyView.
In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen   +11 more
wiley   +1 more source

Tree type-specific endophytic bacterial assembly and function in senescing leaves and needles in temperate forests of Central Europe. [PDF]

BMC Plant Biol
Ji L, Tanunchai B, Schroeter SA, Wahdan SFM, Hossen S, Noll M, Purahong W.   +6 more
europepmc   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

Advanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro, Aldo R. Boccaccini, Nicholas R. Forsyth, Tina P. Dale   +3 more
wiley   +1 more source

Mitochondrial Dynamics Disorder Drives Nucleus Pulposus Cell Senescence in Lumbar Scoliosis of Aging Bipedal Rats Under Asymmetric Force. [PDF]

Stem Cells Int
Wang J, Cao D, Peng J, Zhou X, Liu Z, Wang X, Zhang A, Shen K.   +7 more
europepmc   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

Advanced NanoBiomed Research, EarlyView.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen, Michael B. Nguyen, Elliot Widd, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Houston Harding, Chloe Hurteau, Anika Yogi, Colin Luo, Rebecca L. Braden, Pedro Cabrales, Karen L. Christman   +14 more
wiley   +1 more source

ROS-degradable hydrogel delivering LOXL2-LNPs rescues disc degeneration by synchronously suppressing cellular senescence and oxidative damage. [PDF]

J Nanobiotechnology
Zhang J, Li Y, Ding R, Pan C, Xie J, Huang G, Chen X, Zhao X, Miao X, Cheng X.   +9 more
europepmc   +1 more source

Lower-canopy marcescence facilitates light use efficiency of upper-canopy needles in <i>Cunninghamia lanceolata</i> in southeast China: implications for plant growth-survival trade-offs. [PDF]

Front Plant Sci
Zhou L, Guo J, Zou Z, Chen Y, Liu Q, Li S.   +5 more
europepmc   +1 more source

DEPTOR regulates nucleus pulposus cell senescence through the mTORC1/S6K1/ATG1 pathway to alleviate intervertebral disk degeneration. [PDF]

Cell Death Discov
Lu H, Liu Z, Wang Y, Han S, Zhang X, Liu R, Gao Y, Liu H, Tao H, Ma X, Guo Z.   +10 more
europepmc   +1 more source