Results 131 to 140 of about 8,424,658 (307)

AN ANALYSIS OF EXTENSION NEEDS FOR AGRICULTURAL ECONOMISTS [PDF]

open access: yes
Teaching/Communication/Extension/Profession,
Nesius, Ernest J.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Medical education in times of war: a mixed-methods needs analysis at Ukrainian medical schools. [PDF]

open access: yesBMC Med Educ, 2023
Mayer A   +5 more
europepmc   +1 more source

New technologies in general aviation [PDF]

open access: yes, 2010
This research explored the technological needs of GA pilots at international levels. Overall, single pilot operators tend to value costs as the most important feature of any technology, followed by technology that helps with pre-flight tasks as well as
Diaz Vilela, Luis   +2 more
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Current situation and needs analysis of medical staff first aid ability in China: a cross-sectional study. [PDF]

open access: yesBMC Emerg Med, 2023
Wang J   +9 more
europepmc   +1 more source

A multi-INT semantic reasoning framework for intelligence analysis support [PDF]

open access: yes, 2010
Lockheed Martin Corp. has funded research to generate a framework and methodology for developing semantic reasoning applications to support the discipline oflntelligence Analysis. This chapter outlines that framework, discusses
Herbert, Basik   +3 more
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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