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Xylitol prevents NEFA-induced insulin resistance in rats [PDF]
Diabetologia, 2012 Increased NEFA levels, characteristic of type 2 diabetes mellitus, contribute to skeletal muscle insulin resistance. While NEFA-induced insulin resistance was formerly attributed to decreased glycolysis, it is likely that glucose transport is the rate-limiting defect.
P Kishore, Meredith Hawkins
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Are we waking up to the effects of NEFA? [PDF]
Diabetologia, 2015 NEFA are mobilised from adipose tissues during fasting or stress. Under conditions of acute or chronic NEFA excess, skeletal muscle and hepatic insulin resistance may ensue. Hence, a wealth of literature has focused on the crosstalk between NEFA and glucose in the pathogenesis of insulin resistance.
Jonathan C Jun +2 more
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Origin of the NEFA and Nuc Signal Sequences
Journal of Molecular Evolution, 1998The human protein NEFA binds calcium, contains a leucine zipper repeat that does not form a homodimer, and is proposed (along with the homologous Nuc protein) to have a common evolutionary history with an EF-hand ancestor. We have isolated and characterized the N-terminal domain of NEFA that contains a signal sequence inferred from both endoproteinase ...
A, Karabinos +3 more
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THE KETOTIC RATIO (KB/NEFA) IN MAN
Clinical and Experimental Pharmacology and Physiology, 1981SUMMARY1. The ‘ketotic ratio’, which is defined as the plasma ketone‐body concentration divided by the plasma nonesterified fatty acid concentration, is potentially useful in predicting the magnitude of the ketone response to a given increment in plasma fatty acid concentration.2. Two parameters of the ketotic ratio were studied. First, a comparison of
D S, Schade, R P, Eaton
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Golgi retention of human protein NEFA is mediated by its N-terminal Leu/Ile-rich region
FEBS Letters, 2001 The subcellular localization of the human Ca2+-binding EF-hand/leucine zipper protein NEFA was studied in HeLa cells by immunofluorescence microscopy. Double immunostaining using mouse anti-NEFA monoclonal antibody 1H8D12 and rabbit anti-ERD2 polyclonal ...
Hilde Gotz +2 more
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Effect of a diabetogeic factor from bovine adenohypophysis on dog serum nefa levels
International Journal of Biochemistry & Cell Biology, 1972 1. 1. Fasted dog serum non-esterified fatty acid (NEFA) levels were elevated 10 and 34 hours after administration of a diabetogenic protein (BDF) isolated from bovine adenohypophysis.2. 2.
Gene F Tutwiler
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The influence of fatness on the plasma NEFA response to glucose ingestion
Metabolism, 1967Abstract The response of the plasma NEFA concentration to ingestion of glucose has been studied in 59 people who ranged from very obese to very lean. The results have been treated mathematically by a method of general application, which allows analysis of the relation between the blood glucose and NEFA curves as a whole, and of the influence exerted ...
T, Hanley, J G, Lewis, G J, Knight
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Evaluation of a Rapid Test for NEFA in Bovine Serum
American Association of Bovine Practitioners Conference Proceedings, 2004Excessive or prolonged periparturient negative energy balance (NEB) is an important issue for dairy producers, and may be associated with increased risk of clinical disease and impaired production and reproductive performance. Affected cows commonly have elevated circulating levels of non-esterified fatty acids (NEFA) prior to calving and increased ...
Gooijer, L. +5 more
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'At id quidem nostris moribus nefas habetur'
2021Göttinger Forum für Altertumswissenschaft, Bd.
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