Results 1 to 10 of about 1,040,136 (170)

Serum Nonesterified Fatty Acids and Incident Stroke: The CHS

Journal of the American Heart Association, 2021
Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies.
Alice H. Lichtenstein, Kuan-Hsun Huang
exaly   +3 more sources

Hormonal Responses to a Short Daytime Fast in Children With Beta-Oxidation Disorders. [PDF]

JIMD Rep
ABSTRACT Fasting‐induced cellular energy deficiency and hypoglycemia are well‐known complications of beta‐oxidation disorders. The changes in energy homeostasis during fasting are under hormonal regulation. This aspect of fasting metabolism in beta‐oxidation disorders is not fully characterized.
Olsson D, Halldin M, Haglind CB, Lajic S, Nordenström A.   +4 more
europepmc   +2 more sources

The effects of saturated fatty acid supplements on plasma and milk concentration of fatty acid esters of hydroxy fatty acids in dairy cows [PDF]

JDS Communications
Fatty acid esters of hydroxy fatty acids (FAHFA) are a novel class of bioactive lipids with demonstrated antidiabetic and anti-inflammatory properties in rodent models and humans but have not been investigated in cows.
M. Arif, B.A. Harsch, C. Matamoros, I.J. Salfer, R. Shepardson, K.J. Harvatine   +5 more
doaj   +2 more sources

Sunrouge, an Anthocyanin-Rich Green Tea Cultivar, Attenuates Fat Accumulation and Obesity-Related Metabolic Abnormalities in Western Diet-Fed Mice. [PDF]

Food Sci Nutr
Proposed metabolic effects of Sunrouge tea based on the findings of the present study. Sunrouge contains both catechins, represented by epigallocatechin gallate (EGCG), and anthocyanins, represented by delphinidin‐3‐O‐galactoside (D3Ga). Long‐term intake of Sunrouge attenuated diet‐induced fat accumulation and obesity‐related metabolic abnormalities ...
Ando C, Furukawa K, Someya S, Yang Y, Igarashi M, Yamada S, Jia H, Kato H.   +7 more
europepmc   +2 more sources

Free Fatty Acids Carried by Lipoproteins: Revisiting the Overlooked Cargo. [PDF]

Acta Physiol (Oxf)
ABSTRACT Free fatty acids (FFAs) are hydrophobic and therefore cannot enter the bloodstream at appreciable levels unless they are solubilized by FFA carriers. Albumin has been appreciated for years as the major FFA carrier, but it is not the only carrier.
Henderson GC, Buhman KK, Tomoo K.
europepmc   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long-chain fatty acid accumulation after myocardial ischemia-reperfusion in mice. [PDF]

FEBS Open Bio
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Gauvin J, Radmannia N, Huynh DN, Ménard L, Daneault C, Veilleux M, Ahsanullah A, Carpentier AC, Lubell WD, Ruiz M, Ong H, Marleau S, Gravel SP.   +12 more
europepmc   +2 more sources

Deep Eutectic Solvent as Dual Solvent-Catalyst for Efficient Starch Esterification With Vinyl Laurate via Reactive Extrusion. [PDF]

ChemSusChem
A green approach to esterify wheat starch by reactive extrusion using a novel deep eutectic solvent has been developed. The DES acted both as a starch solvent and as an activating agent to complete the esterification within 15–30 min. This novel approach opens new opportunities for the development and upscaling of biobased polymers with promising ...
Bouzidi S, Najahi A, Lévêque JM, Chaud P, Hugenell F, Magnin A, Molina-Boisseau S, Putaux JL, Boufi S.   +8 more
europepmc   +2 more sources

Very long-chain fatty acids are accumulated in triacylglycerol and nonesterified forms in colorectal cancer tissues

Scientific Reports, 2021
Colorectal cancer (CRC) is a major cancer, and its precise diagnosis is especially important for the development of effective therapeutics. In a series of metabolome analyses, the levels of very long chain fatty acids (VLCFA) were shown to be elevated in
Kotaro Hama, Yuko Fujiwara, Tamuro Hayama, Tsuyoshi Ozawa, Keijiro Nozawa, Keiji Matsuda, Yojiro Hashiguchi, Kazuaki Yokoyama   +7 more
doaj   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Substrate modulation of fatty acid effects on energization and respiration of kidney proximal tubules during hypoxia/reoxygenation. [PDF]

PLoS ONE, 2014
Kidney proximal tubules subjected to hypoxia/reoxygenation develop a nonesterified fatty acid-induced energetic deficit characterized by persistent partial mitochondrial deenergization that can be prevented and reversed by citric acid cycle substrates ...
Anja Bienholz, Ahmad Al-Taweel, Nancy F Roeser, Andreas Kribben, Thorsten Feldkamp, Joel M Weinberg   +5 more
doaj   +1 more source