Results 41 to 50 of about 1,040,136 (170)

Nonesterified fatty acids and lipid peroxidation

, 1992
Oxygen free radicals damage cells through peroxidation of membrane lipids. Gastrointestinal mucosal membranes were found to be resistant to in vitro lipid peroxidation as judged by malonaldehyde and conjugated diene production and arachidonic acid ...
Nalini, S., Manohar, M., Balasubramanian, K. A.   +2 more
core   +1 more source

Effects of a high-fat diet on the growth performance, lipid metabolism, and the fatty acids composition of liver and skin fat in Pekin ducks aged from 10 to 40 days

Poultry Science, 2023
: This study aimed to investigate the effect of a high-fat diet on the growth performance, serum, liver, and skin lipid metabolism as well as the fatty acids composition of liver and skin fat in Pekin ducks from 10 to 40 d of age based on a pair-fed ...
G.H. Chen, K.Y. Zhang, G. Tian, S.P. Bai, X.M. Ding, J.P. Wang, L. Lv, Y. Xuan, Q.F. Zeng   +8 more
doaj   +1 more source

PDE4D and PDE3B orchestrate distinct cAMP microdomains in 3T3‐L1 adipocytes

British Journal of Pharmacology, EarlyView.
Basal conditions: •Ins/PDE3B lowers cytoplasmic cAMP (cyt‐cAMP) without affecting plasma membrane cAMP (pm‐cAMP). •Insulin decreases lipid droplet cAMP (LD‐cAMP) independent of PDE3B. •FGF1/PDE4D modestly reduces both cyt‐ and pm‐cAMP, while PDE4D alone can modulate LD‐cAMP. ISO stimulation: •Ins/PDE3B has minimal impact on cyt‐cAMP.
Johannes Krier, David Spähn, David Arturo Juarez Lopez, Judith L. Nono, Judith Seigner, Lisa Jacob, Siegfried Ussar, Robert Lukowski, Andreas L. Birkenfeld, Gencer Sancar   +9 more
wiley   +1 more source

Type 1 diabetes in the era of obesity: Pathophysiology and therapeutic implications

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Type 1 diabetes is defined by immune‐mediated beta‐cell failure and dependence on exogenous insulin. That definition is correct, but it may not fully describe many people seen in current clinical practice. Overweight and obesity are now common in type 1 diabetes, leading to variable combinations of high insulin requirement, hypertension ...
Zachary Bloomgarden
wiley   +1 more source

The Staphylococcus aureus Response to Unsaturated Long Chain Free Fatty Acids: Survival Mechanisms and Virulence Implications. [PDF]

, 2009
Staphylococcus aureus is an important human commensal and opportunistic pathogen responsible for a wide range of infections. Long chain unsaturated free fatty acids represent a barrier to colonisation and infection by S.
Horsburgh Malcolm J., Ward, D, Rees, HH, Ward Deborah, Elisabet Josefsson, Kenny John G., Lindsay Jodi A., John G Kenny, Tarkowski Andrej, Horsburgh, MJ, Hinds Jason, Jonsson Ing-Marie, Ing-Marie Jonsson, Huw H Rees, Deborah Ward, Josefsson Elisabet, Tarkowski, A, Lindsay, JA, Malcolm J Horsburgh, Josefsson, E, Kenny, JG, Hinds, J, Jodi A Lindsay, Rees Huw H., Jason Hinds, Andrej Tarkowski, Jonsson, IM   +26 more
core   +2 more sources

Impact of Sleep on Glucose Metabolism in Individuals With Overweight or Obesity: A Systematic Review

Obesity Reviews, EarlyView.
ABSTRACT Introduction The obesity epidemic has coincided with chronic sleep deprivation. Sleep disturbances may contribute to metabolic dysfunction in individuals with BMI ≥ 25 kg/m2. This review investigates associations between sleep patterns and glucose metabolism in this population.
Trudy Abla Sitsofe Accorley, Patricia Casas‐Agustench, Gail Rees, Kathy Redfern   +3 more
wiley   +1 more source

Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period

Journal of Lipid Research, 2003
Circulating triacylglycerol (TG) arises mainly from dietary fat. However, little is known about the entry of dietary fat into the major TG pool, very low-density lipoprotein (VLDL) TG. We used a novel method to study the specific incorporation of dietary
Richard B. Heath, Fredrik Karpe, Ross W. Milne, Graham C. Burdge, Stephen A. Wootton, Keith N. Frayn   +5 more
doaj   +1 more source

Induction of lipid oxidation by polyunsaturated fatty acids of marine origin in small intestine of mice fed a high-fat diet [PDF]

, 2009
Background. Dietary polyunsaturated fatty acids (PUFA), in particular the long chain marine fatty acids docosahexaenoic (DHA) and eicosapentaenoic (EPA), are linked to many health benefits in humans and in animal models.
Schothorst, E.M., van, Evert M van Schothorst, Annelies Bunschoten, Jaap Keijer, van Schothorst, E.M., Molthoff, J.W., Keijer, J., Flachs, P., Bunschoten, A., Kopecky, J., Vink, C., Franssen-Hal, N.L.W., van, van Franssen-Hal, N.L.W., Ondrej Kuda, Carolien Vink, Nicole LW Franssen-van Hal, Guido JEJ Hooiveld, Pavel Flachs, Kuda, O., Hooiveld, G.J.E.J., Jan Kopecky, Jos Molthoff   +21 more
core   +1 more source

The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism

, 1992
Eicosanoids, in particular prostaglandin E2 (PGE2), are potent inhibitors of a number of immune responses, including lymphocyte proliferation. We have previously shown that fatty acids, especially polyunsaturated fatty acids (PUFA), inhibit mitogen ...
Calder, P.C., Newsholme, E.A., Bevan, S.J.   +2 more
core   +1 more source

Cell-associated nonesterified fatty acid levels and their alteration during lipolysis in the isolated mouse adipose cell

Journal of Lipid Research, 1973
A rapid and flexible method has been developed for measuring cell-associated, probably intracellular, nonesterified fatty acids (CAFA) in isolated mouse adipose cells. A variety of lipolytic agents as well as various concentrations of epinephrine elevate
Samuel W. Cushman, Jerrold J. Heindel, Bernard Jeanrenaud   +2 more
doaj   +1 more source