Results 51 to 60 of about 1,040,136 (170)

Reduced Plasma Nonesterified Fatty Acid Levels and the Advent of an Acute Lung Injury in Mice after Intravenous or Enteral Oleic Acid Administration

Mediators of Inflammation, 2012
Although exerting valuable functions in living organisms, nonesterified fatty acids (NEFAs) can be toxic to cells. Increased blood concentration of oleic acid (OLA) and other fatty acids is detected in many pathological conditions.
Cassiano Felippe Gonçalves de Albuquerque, Patrícia Burth, Mauricio Younes Ibrahim, Diogo Gomes Garcia, Patrícia Torres Bozza, Hugo Caire Castro Faria Neto, Mauro Velho Castro Faria   +6 more
doaj   +1 more source

Adipocyte‐Derived KIF13B Aggravates Obesity‐Associated Metabolic Dysfunction via LRP1/PPARγ Signaling

MedComm, Volume 7, Issue 10, October 2026.
Adipocyte‐derived KIF13B promotes LRP1 localization and nuclear LRP1–PPARγ transcriptional activity, thereby enhancing adipogenic gene expression, lipid accumulation, and obesity‐associated metabolic dysfunction. Adipocyte‐specific Kif13b deletion disrupts this LRP1/PPARγ axis, suppresses adipogenic programming, reduces adipose expansion, and protects ...
Guolin Miao, Zhaoling Li, Lianxin Zhang, Yitong Xu, Ziwei Wang, Zixun Wang, Aiden Xian, Liwen Zheng, Jingxuan Chen, Yufei Han, Chunhua Shan, Kaikai Lu, Ming Tao, Ling Zhang, Weiguang Zhang, Wei Huang, Yuhui Wang, Rui Wei, Erdan Dong, Xunde Xian   +19 more
wiley   +1 more source

Metabolomics of dietary fatty acid restriction in patients with phenylketonuria [PDF]

, 2012
Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA).
Berthold Koletzko (144194), Thiery, Joachim, Berthold Koletzko, Bruegel Mathias, Linda Kortz, Kiess Wieland, Beblo, Skadi, Kortz, Linda, Kortz Linda, Linda Kortz (144188), Wieland Kiess (102793), Uta Ceglarek (144203), Skadi Beblo (144186), Claudia Matthies (144191), Kiess, Wieland, Bruegel, Mathias, Mathias Bruegel (144197), Wieland Kiess, Beblo Skadi, Ulrike Mütze, Koletzko Berthold, Skadi Beblo, Ceglarek Uta, Ceglarek, Uta, Ulrike Mütze (144183), Joachim Thiery, Joachim Thiery (66414), Rohde, Carmen, Matthies, Claudia, Matthies Claudia, Rohde Carmen, Uta Ceglarek, Mütze, Ulrike, Koletzko, Berthold, Mathias Bruegel, Carmen Rohde, Carmen Rohde (144200), Thiery Joachim, Mütze Ulrike, Claudia Matthies   +39 more
core   +2 more sources

Circulating Non-Esterified Fatty Acids as Biomarkers for Fat Content and Composition in Pigs

Animals, 2021
Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat ...
Marc Tor, Francesca Vilaró, Roger Ros-Freixedes, Javier Álvarez-Rodríguez, Lluís Bosch, Sofia Gol, Ramona N. Pena, Josep Reixach, Joan Estany   +8 more
doaj   +1 more source

Plasma free fatty acid levels influence Zn2+-dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin [PDF]

, 2014
Background: Histidine-rich glycoprotein (HRG) regulates coagulation, through its ability to bind and neutralize heparins. HRG associates with zinc ions (Zn2+) to stimulate HRG-heparin complex formation. Under normal conditions the majority of plasma Zn2+
Schwarz-Linek, Ulrich, Blindauer, Claudia A, Stewart, Alan J., Blindauer, Claudia A., Kassaar, Omar   +4 more
core   +1 more source

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

The Journal of Pathology, Volume 270, Issue 1, Page 98-113, September 2026.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan, Piper Moore, Rohan Varshney, Miles Montegut, Qiannan Ma, Kayla Klatt, Reshmi Parameswaran, Elif G Ertugral, Chandrasekhar R Kothapalli, Michael C Rudolph, Radhika P Atit   +10 more
wiley   +1 more source

Placental transfer of long-chain polyunsaturated fatty acids (LC-PUFA) [PDF]

, 2007
Considerable evidence exists for marked beneficial effects of omega-3 long-chain polyunsaturated fatty acids (LC-PUFA) during pregnancy. The omega-3 LCPUFA docosahexaenoic acid (DHA) is incorporated in large amounts in fetal brain and other tissues ...
Hans Demmelmair, Elvira Larqué, Berthold Koletzko, Koletzko, Berthold, Larqué, Elvira, Demmelmair, Hans   +5 more
core   +2 more sources

Characterization of milk fatty acids based on genetic and herd parameters [PDF]

, 2012
The objective of this study was to characterize the fatty acids (FA) in milk based on genetic and herd parameters to investigate the origin of the different FA in milk.
Bovenhuis, H., Dijkstra, J., Hooijdonk, A.C.M., van, Valenberg, H.J.F., van, Heck, J.M.L.   +4 more
core   +1 more source

Incorporation of cis-9,trans-11 or trans-10,cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men

Journal of Lipid Research, 2004
This study investigated the incorporation of cis-9,trans-11 conjugated linoleic acid (c9,t11 CLA) and trans-10,cis-12-CLA (t10,c12 CLA) into plasma and peripheral blood mononuclear cell (PBMC) lipids when consumed as supplements highly enriched in these ...
Graham C. Burdge, Berit Lupoli, Jennifer J. Russell, Sabine Tricon, Samantha Kew, Tapati Banerjee, Kevin J. Shingfield, David E. Beever, Robert F. Grimble, Christine M. Williams, Parveen Yaqoob, Philip C. Calder   +11 more
doaj   +1 more source

Aerobic Exercise Training Increases Circulating sRAGE in Adults With Type 2 Diabetes: Associations With Sheddase Regulation

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8157-8171, September 2026.
ABSTRACT Objective Soluble receptor for advanced glycation end‐products (sRAGE) and soluble Toll‐like receptor 4 (sTLR4) are circulating pattern recognition receptor isoforms implicated in inflammatory regulation in type 2 diabetes mellitus (T2DM). This study examined the effects of supervised aerobic exercise training (AET) on circulating sRAGE, sTLR4,
Ryan K. Perkins, Corey E. Mazo, James Shadiow, Pallavi Varshney, Edwin R. Miranda, Victoria R. Miranda, Maggie Eisenberg, Jane E. Nakamura, Elif A. Oral, Jacob M. Haus   +9 more
wiley   +1 more source