Results 61 to 70 of about 14,053 (222)

Platelet‐Activating Factor Pathway in Women With Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity

Obesity, Volume 34, Issue 5, Page 1056-1067, May 2026.
Increased hepatic PAFR expression in MASLD is associated with histological disease severity and may contribute to progression through platelet activation, whereas circulating Lp‐PLA2 levels lack discriminatory value as a noninvasive biomarker. ABSTRACT Objective This study aimed to investigate the platelet‐activating factor (PAF) pathway in obesity ...
Joan Duran‐Bertran, Helena Clavero‐Mestres, Razieh Mahmoudian, Sara Muñiz‐Piera, Carmen Aguilar, David Riesco, Javier Camaron, Salomé Martínez, Margarida Vives, Marta París, Fàtima Sabench, Teresa Auguet   +11 more
wiley   +1 more source

Circulating Non-Esterified Fatty Acids as Biomarkers for Fat Content and Composition in Pigs

Animals, 2021
Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat ...
Marc Tor, Francesca Vilaró, Roger Ros-Freixedes, Javier Álvarez-Rodríguez, Lluís Bosch, Sofia Gol, Ramona N. Pena, Josep Reixach, Joan Estany   +8 more
doaj   +1 more source

Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]

, 2014
Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin, Cho, Kae Won, Cozacov, Zoharit, Hu, Chun-Rui, Li, Siming, Lin, Jiandie D, Lumeng, Carey N, Saltiel, Alan R, Uhm, Maeran, Wang, Guo-Xiao, Xu, Acer E   +10 more
core   +2 more sources

C/EBP α is Essential for Gonadal but Not Inguinal White Adipose Tissue Formation in Mice

Obesity, Volume 34, Issue 4, Page 882-895, April 2026.
Human genetics has linked the gene CEBPA to waist to hip ratio and adipose distribution. We generated mice with AdipoQ‐Cre driven deletion of Cebpa and found these mice to have a specific reduction in gonadal white adipose tissue and myriad other metabolic phenotypes.
Krista Y. Hu, Yu‐Lin Ma, Esme A. Dodge, Olivia A. B. Maguire, Caio V. Matias, Ryan P. Barney, Hector S. Himede, Juliana Gomez Pardo, Miriam Cepeda, Scott M. Gordon, Robert C. Bauer   +10 more
wiley   +1 more source

Antiresistin RNA oligonucleotide ameliorates diet-induced nonalcoholic fatty liver disease in mice through attenuating proinflammatory cytokines [PDF]

, 2015
© 2015 Yi Tan et al. The aim of this study was to determine whether inhibition of resistin by a synthetic antiresistin RNA (oligonucleotide) oligo ameliorates metabolic and histological abnormalities in nonalcoholic fatty liver disease (NAFLD) induced by
Jin, XL, Kim, J, Lao, W, Qu, X, Tan, Y, Xiao, L   +5 more
core   +4 more sources

Incorporation of cis-9,trans-11 or trans-10,cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men

Journal of Lipid Research, 2004
This study investigated the incorporation of cis-9,trans-11 conjugated linoleic acid (c9,t11 CLA) and trans-10,cis-12-CLA (t10,c12 CLA) into plasma and peripheral blood mononuclear cell (PBMC) lipids when consumed as supplements highly enriched in these ...
Graham C. Burdge, Berit Lupoli, Jennifer J. Russell, Sabine Tricon, Samantha Kew, Tapati Banerjee, Kevin J. Shingfield, David E. Beever, Robert F. Grimble, Christine M. Williams, Parveen Yaqoob, Philip C. Calder   +11 more
doaj   +1 more source

Maximal Oxidative Capacity during Exercise Is Associated with Skeletal Muscle Fuel Selection and Dynamic Changes in Mitochondrial Protein Acetylation [PDF]

, 1995
SummaryMaximal exercise-associated oxidative capacity is strongly correlated with health and longevity in humans. Rats selectively bred for high running capacity (HCR) have improved metabolic health and are longer-lived than their low-capacity ...
Overmyer, Katherine A., Evans, Charles R., Qi, Nathan R., Minogue, Catherine E., Carson, Joshua J., Chermside-Scabbo, Christopher J., Koch, Lauren G., Britton, Steven L., Pagliarini, David J., Coon, Joshua J., Burant, Charles F.   +10 more
core   +1 more source

The Double‐Edged Sword of Gestational Insulin Resistance: Navigating Maternal Adaptation and Its Risks for Pregnancy and Offspring Health

Obesity Reviews, Volume 27, Issue 4, April 2026.
ABSTRACT Although much research focuses on the effects of hyperglycemia during pregnancy on maternal and offspring health, this narrative review specifically centers on the role of insulin resistance (IR) in pregnancy complications and offspring long‐term health.
Runyu Du, Fei Wang, Ling Li, Qiuyue Wang
wiley   +1 more source

Upcycling Agricultural By‐Product: Therapeutic Potential of Oriental Melon Stem (Cucumis melo var. makuwa) in Treating Obesity and Fatty Liver via Enhanced Thermogenesis

Food Frontiers, Volume 7, Issue 2, March 2026.
This study proposes the upcycling of oriental melon (Cucumis melo var. makuwa) stems, typically discarded as agricultural waste, into a bioactive extract with functional potential. CMSE ameliorates high‐fat‐diet‐induced obesity and fatty liver, contributing to the restoration of metabolic health by enhancing the expression of thermogenesis‐related ...
Myeong‐Jin Kim, Ji Yun Van, Su‐Yeon Park, Ji Young Hwang, Yerin Seong, Yeo Jin Park, Seokmin Lee, Bo‐mi Ryu, Joo Yun Jun, Won‐Kyo Jung, Bonggi Lee   +10 more
wiley   +1 more source

Plasma Levels of Free Fatty Acids in Women with Gestational Diabetes and Its Intrinsic and Extrinsic Determinants: Systematic Review and Meta-Analysis

Journal of Diabetes Research, 2019
Background. Free fatty acids, also known as nonesterified fatty acids, are proinflammatory molecules that induce insulin resistance in nonpregnant individuals.
Jose Rafael Villafan-Bernal, Mariana Acevedo-Alba, Rodrigo Reyes-Pavon, Guillermo Andres Diaz-Parra, Diana Lucia Lip-Sosa, Hilda Imelda Vazquez-Delfin, Martha Hernandez-Muñoz, Daniel Ely Bravo-Aguirre, Francesc Figueras, Raigam Jafet Martinez-Portilla   +9 more
doaj   +1 more source