Results 61 to 70 of about 637,805 (212)
OPA1 in MC4R Neurons Regulates Dietary Fat Intake and Body Weight in Mice
The FASEB Journal, Volume 40, Issue 10, 31 May 2026.Soybean oil intake induces OPA1 expression in hypothalamic MC4R neurons, contributing to adaptive regulation of appetite. MC4R neuron‐specific OPA1 deficiency increases soybean oil consumption and leads to obesity, with a more pronounced effect in females.
Shigenobu Matsumura +10 more
wiley +1 more source
Animal Research and One Health, Volume 4, Issue 2, Page 198-212, May 2026.(1) Kbhb modification of FBP1 and PCK1 is involved in regulation of the gluconeogenesis pathway. (2) Kbhb of FBP1 and PCK1 is catalyzed by p300 and removed by HDACs. (3) BHB induced an increase in the enzymatic activity of FBP1 and PCK1 through Kbhb modification at the K43 site of FBP1 and the K191 site of PCK1.
DingPing Feng +6 more
wiley +1 more source
American Journal of Clinical Nutrition, 2018 Background Acute inflammation, and subsequent release of bacterial products (e.g. LPS), inflammatory cytokines, and stress hormones, is catabolic, and the loss of lean body mass predicts morbidity and mortality.
H. H. Thomsen +6 more
semanticscholar +1 more source
Journal of Lipid Research, 2004 This study investigated the incorporation of cis-9,trans-11 conjugated linoleic acid (c9,t11 CLA) and trans-10,cis-12-CLA (t10,c12 CLA) into plasma and peripheral blood mononuclear cell (PBMC) lipids when consumed as supplements highly enriched in these ...
Graham C. Burdge +11 more
doaj +1 more source
Nonesterified Fatty Acids and Hepatic Glucose Metabolism in the Conscious Dog [PDF]
Diabetes, 2004 We used tracer and arteriovenous difference techniques in conscious dogs to determine the effect of nonesterified fatty acids (NEFAs) on net hepatic glucose uptake (NHGU). The protocol included equilibration ([3-3H]glucose), basal, and two experimental periods (−120 to −30, −30 to 0, 0–120 [period 1], and 120–240 min [period 2], respectively).
Mary Courtney, Moore +6 more
openaire +2 more sources
GLP‐1 agonists and the gut microbiome: A bidirectional relationship
British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1309-1325, May 2026.Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath +2 more
wiley +1 more source
Diabetes, 2011 OBJECTIVE Postprandial plasma nonesterified fatty acid (NEFA) appearance is increased in type 2 diabetes. Our objective was to determine whether skeletal muscle uptake of plasma NEFA is abnormal during the postprandial state in type 2 diabetes.
Sébastien M. Labbé +8 more
semanticscholar +1 more source
Journal of Diabetes Research, 2019 Background. Free fatty acids, also known as nonesterified fatty acids, are proinflammatory molecules that induce insulin resistance in nonpregnant individuals.
Jose Rafael Villafan-Bernal +9 more
doaj +1 more source
Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.We applied a latent class mixed model to cluster individuals based on their postprandial triglyceride response curves after consumption of high‐fat meals. Three clusters with different triglyceride response patterns were identified. This approach holds the potential to be used for identifying metabolically dysfunctional individuals.
Jiaying Hu +5 more
wiley +1 more source
Disturbed bovine mitochondrial lipid metabolism: a review
Veterinary Quarterly, 2017 In mammals, excess energy is stored primarily as triglycerides, which are mobilized when energy demands arise and cannot be covered by feed intake. This review mainly focuses on the role of long chain fatty acids in disturbed energy metabolism of the ...
J. H. (Han) van der Kolk +3 more
doaj +1 more source