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Serum Nonesterified Fatty Acids and Incident Stroke: The CHS [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies.
Neil K. Huang +7 more
doaj +7 more sources
Association between plasma nonesterified fatty acids species and adipose tissue fatty acid composition. [PDF]
PLoS ONE, 2013 Fatty acid composition of adipose tissue (AT) is an established long-term biomarker for fatty acid (FA) intake and status, but AT samples are not easily available.
Christian Hellmuth +5 more
doaj +3 more sources
Nonesterified Fatty Acids, Albumin, and Platelet Aggregation [PDF]
Diabetes, 2015 It has been known for five decades that nonesterified fatty acids (NEFAs) have a role in the activation of platelets and thrombosis. Thus, the infusion of NEFAs leads to massive thrombosis and platelet activation (1–4). It has also been shown that their binding to albumin protects the platelets from activation (5).
Sandeep Dhindsa, Husam Ghanim
exaly +4 more sources
Plasma Fatty Acid–Binding Protein 4, Nonesterified Fatty Acids, and Incident Diabetes in Older Adults [PDF]
Diabetes Care, 2012 OBJECTIVE To examine the relation of fatty acid–binding protein (FABP)4 and nonesterified fatty acids (NEFAs) to diabetes in older adults. RESEARCH DESIGN AND METHODS We ascertained incident diabetes among 3,740 Cardiovascular Health Study participants ...
Jorge R Kizer, Russell Tracy
exaly +3 more sources
Scientific Reports, 2021 Colorectal cancer (CRC) is a major cancer, and its precise diagnosis is especially important for the development of effective therapeutics. In a series of metabolome analyses, the levels of very long chain fatty acids (VLCFA) were shown to be elevated in
Kotaro Hama +7 more
doaj +2 more sources
Serum Individual Nonesterified Fatty Acids and Risk of Heart Failure in Older Adults. [PDF]
Cardiology, 2021 Background: Heart failure (HF) is highly prevalent among older adults and is associated with high costs. Although serum total nonesterified fatty acids (NEFAs) have been positively associated with HF risk, the contribution of each individual NEFA to HF ...
Djousse L +11 more
europepmc +2 more sources
Nonesterified Fatty Acids and Depression in Cancer Patients and Caregivers. [PDF]
Curr Dev Nutr, 2020 Nonesterified fatty acids (NEFAs) are known to have inflammatory effects. The inflammatory hypothesis of depression suggests that omega-3 (ω-3) and omega-6 (ω-6) fatty acids might be negatively and positively correlated with depression, respectively.An exploratory study was conducted to determine the association between dietary free fatty acids and ...
McCusker MR +6 more
europepmc +4 more sources
Quantitative extraction and determination of nonesterified fatty acids in plasma
Journal of Lipid Research, 1973 A method is described for the determination of nonesterified fatty acids in plasma. Extraction is at least 98% efficient, and losses during subsequent stages are corrected for by the use of an internal radioactive standard.
W.G. Duncombe, T.J. Rising
doaj +3 more sources
Diabetes, 2011 OBJECTIVE Postprandial plasma nonesterified fatty acid (NEFA) appearance is increased in type 2 diabetes. Our objective was to determine whether skeletal muscle uptake of plasma NEFA is abnormal during the postprandial state in type 2 diabetes.
André Carpentier +2 more
exaly +2 more sources
The effects of saturated fatty acid supplements on plasma and milk concentration of fatty acid esters of hydroxy fatty acids in dairy cows [PDF]
JDS CommunicationsFatty acid esters of hydroxy fatty acids (FAHFA) are a novel class of bioactive lipids with demonstrated antidiabetic and anti-inflammatory properties in rodent models and humans but have not been investigated in cows.
M. Arif +5 more
doaj +2 more sources