Results 21 to 30 of about 637,805 (212)

Effects of timing of abomasal infusion of fatty acids on the daily rhythms of milk synthesis and plasma hormones and metabolites in dairy cows [PDF]

Journal of Dairy Science
: Dairy cows display daily rhythms of milk synthesis that appear to be driven by a circadian clock located in the mammary gland. These rhythms are altered by the time of feed availability. Fatty acids have been shown to entrain circadian rhythms in liver
I.J. Salfer, P.A. Bartell, K.J. Harvatine   +2 more
doaj   +2 more sources

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Substrate modulation of fatty acid effects on energization and respiration of kidney proximal tubules during hypoxia/reoxygenation. [PDF]

PLoS ONE, 2014
Kidney proximal tubules subjected to hypoxia/reoxygenation develop a nonesterified fatty acid-induced energetic deficit characterized by persistent partial mitochondrial deenergization that can be prevented and reversed by citric acid cycle substrates ...
Anja Bienholz, Ahmad Al-Taweel, Nancy F Roeser, Andreas Kribben, Thorsten Feldkamp, Joel M Weinberg   +5 more
doaj   +1 more source

Regulation of Insulin Clearance by Non-Esterified Fatty Acids

Biomedicines, 2022
Insulin stores lipid in adipocytes and prevents lipolysis and the release of non-esterified fatty acids (NEFA). Excessive release of NEFA during sustained energy supply and increase in abdominal adiposity trigger systemic insulin resistance, including in
Sonia M. Najjar, Raziyeh Abdolahipour, Hilda E. Ghadieh, Marziyeh Salehi Jahromi, John A. Najjar, Basil A. M. Abuamreh, Sobia Zaidi, Sivarajan Kumarasamy, Harrison T. Muturi   +8 more
doaj   +1 more source

Heritability estimates of predicted blood β-hydroxybutyrate and nonesterified fatty acids and relationships with milk traits in early-lactation Holstein cows.

Journal of Dairy Science, 2020
At the beginning of lactation, high-producing cows commonly experience an unbalanced energy status that is often responsible for the onset of metabolic disorders and impaired health and performance.
A. Benedet, A. Costa, M. Marchi, M. Penasa   +3 more
semanticscholar   +1 more source

Sirtuin 3 improves fatty acid metabolism in response to high nonesterified fatty acids in calf hepatocytes by modulating gene expression.

Journal of Dairy Science, 2020
Sirtuin 3 (SIRT3), a mitochondrial deacetylase, is a key regulator of energy metabolism in the liver. In nonruminants, the hepatic abundance of SIRT3 is decreased in individuals with nonalcoholic fatty liver diseases, and recovery of SIRT3 alleviates ...
Leihong Liu, D. Xing, Xiliang Du, Tao Peng, J. McFadden, L. Wen, Hongyu Lei, W. Dong, Guowen Liu, Zhe Wang, Jianming Su, Jianhua He, Xinwei Li   +12 more
semanticscholar   +1 more source

Serum individual non-esterified fatty acids and risk of heart failure in older adults

The Cardiology, 2021
Background: Heart failure (HF) is highly prevalent among older adults and is associated with high costs. Although serum total nonesterified fatty acids (NEFAs) have been positively associated with HF risk, the contribution of each individual NEFA to HF ...
L. Djoussé, M. Biggs, N. Matthan, Joachim H. Ix, A. Fitzpatrick, I. King, R. Lemaitre, B. McKnight, J. Kizer, A. Lichtenstein, K. Mukamal, D. Siscovick   +11 more
semanticscholar   +1 more source

Demonstration of two pools of albumin-bound fatty acids

Journal of Lipid Research, 1975
The uptakes of albumin-bound nonesterified fatty acids and of [1-14C]palmitic acid complexed to albumin by the isolated perfused rat liver were compared. During perfusion, the rate of uptake of nonesterified fatty acids decreased and became zero when the
C. Soler-Argilaga, R. Infante, J. Polonovski   +2 more
doaj   +1 more source

Perceptual Quality of Nonesterified Fatty Acids Varies with Fatty Acid Chain Length

Chemical Senses, 2021
Abstract Nonesterified fatty acids (NEFA) are effective taste stimuli. The quality they impart has not been well characterized. Sourness, and “fattiness” have been reported, but an irritation component has also been described and how these transition with gradations of aliphatic chain length has not been systematically studied.
Eunjin Cheon, Richard D Mattes
openaire   +2 more sources

The Role of TCA Cycle Anaplerosis in Ketosis and Fatty Liver in Periparturient Dairy Cows

Animals, 2015
The transition to lactation period in dairy cattle is characterized by metabolic challenges, negative energy balance, and adipose tissue mobilization. Metabolism of mobilized adipose tissue is part of the adaptive response to negative energy balance in ...
Heather M. White
doaj   +1 more source