Results 11 to 20 of about 14,053 (222)

Fat Oxidation, But Not Subcutaneous Adipose Tissue Lipolysis, Differs Between Males and Females During a Treadmill-Based Heat Tolerance Test. [PDF]

Eur J Sport Sci
ABSTRACT This study aimed to determine whether fat metabolism differs between males and females when exposed to extreme exercise‐heat stress. Physically active males (n = 11, 23 ± 4 years, 81.7 ± 11.8 kg, body fat 16.4 ± 6.6%) and females (n = 13, 25 ± 4 years, 60.4 ± 7.1 kg, 24.4 ± 6.7%) completed a 2‐h exercise‐heat tolerance test (40° $\boldsymbol{{}
Morrissey-Basler MC, Szymanski MR, Filep EM, Langan SP, Ormsbee MJ, Lee EC, Casa DJ.   +6 more
europepmc   +2 more sources

Acyl-CoA Binding Protein in White and Brown Adipose Tissue Is Dispensable for Systemic Energy Metabolism in Mice. [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
Nørremark MF, Petersen R, Ruppert PMM, Jul ES, Doktor TK, Nielsen R, Kappel JF, Larsen S, Kornfeld JW, Mandrup S, Andresen BS, Havelund J, Neess D, Færgeman NJ.   +13 more
europepmc   +2 more sources

Comparative analysis of metabolic and functional cardiac alterations in diet- and genetically induced mouse models of cardiac dysfunction. [PDF]

FEBS J
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Ott C, Baumgarten P, Henning T, Weber D, Wallach I, Grune J, Kintscher U, Holzhütter HG, Grune T, Berndt N.   +9 more
europepmc   +2 more sources

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Perceptual Quality of Nonesterified Fatty Acids Varies with Fatty Acid Chain Length

Chemical Senses, 2021
Abstract Nonesterified fatty acids (NEFA) are effective taste stimuli. The quality they impart has not been well characterized. Sourness, and “fattiness” have been reported, but an irritation component has also been described and how these transition with gradations of aliphatic chain length has not been systematically studied.
Eunjin Cheon, Richard D Mattes
openaire   +2 more sources

Proximal Tubule-Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting. [PDF]

FASEB J
Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Aomura D, Nimura T, Yamaka K, Yamada Y, Harada M, Nakajima T, Kimura T, Hashimoto K, Kanno H, Yanagita M, Gonzalez FJ, Tanaka N, Kamijo Y.   +12 more
europepmc   +2 more sources

Chia Oil Supplementation Attenuates Obesity-Induced Hepatic Steatosis, PVAT Inflammation, and Endothelial Dysfunction in Mice. [PDF]

Mol Nutr Food Res
We studied whether chia oil, rich in healthy omega‐3 fats, could improve health in obese mice. The oil reduced fat accumulation in the liver, decreased inflammation around blood vessels, and helped blood vessels relax better. These results suggest chia oil may help prevent complications of obesity, like fatty liver and heart disease.
de Assis-Ferreira A, Muniz-Cassuce G, Fonte-Faria T, de Souza T, Citelli M, de Carvalho LCRM, Ognibene DT, de Bem GF, Resende AC, Barja-Fidalgo C, Vargas da Silva S.   +10 more
europepmc   +2 more sources

Demonstration of two pools of albumin-bound fatty acids

Journal of Lipid Research, 1975
The uptakes of albumin-bound nonesterified fatty acids and of [1-14C]palmitic acid complexed to albumin by the isolated perfused rat liver were compared. During perfusion, the rate of uptake of nonesterified fatty acids decreased and became zero when the
C. Soler-Argilaga, R. Infante, J. Polonovski   +2 more
doaj   +1 more source

In vitro effects of nonesterified fatty acids on bovine neutrophils oxidative burst and viability [PDF]

, 2006
An in vitro study was conducted to examine the influence of nonesterified fatty acids (NEFA) on bovine polymorphonuclear leukocytes (PMN). Eight healthy, midlactating Holstein cows were used as blood donors.
BERNABUCCI, U, Burvenich, Christian, Demeyere, Kristel, Duchateau, Luc, LACETERA, N, SCALIA, D   +5 more
core   +1 more source

The Role of TCA Cycle Anaplerosis in Ketosis and Fatty Liver in Periparturient Dairy Cows

Animals, 2015
The transition to lactation period in dairy cattle is characterized by metabolic challenges, negative energy balance, and adipose tissue mobilization. Metabolism of mobilized adipose tissue is part of the adaptive response to negative energy balance in ...
Heather M. White
doaj   +1 more source