Serum Nonesterified Fatty Acids and Incident Stroke: The CHS [PDF]
Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies.
Neil K. Huang +7 more
doaj +5 more sources
Colorectal cancer (CRC) is a major cancer, and its precise diagnosis is especially important for the development of effective therapeutics. In a series of metabolome analyses, the levels of very long chain fatty acids (VLCFA) were shown to be elevated in
Kotaro Hama +7 more
doaj +2 more sources
The effects of saturated fatty acid supplements on plasma and milk concentration of fatty acid esters of hydroxy fatty acids in dairy cows [PDF]
Fatty acid esters of hydroxy fatty acids (FAHFA) are a novel class of bioactive lipids with demonstrated antidiabetic and anti-inflammatory properties in rodent models and humans but have not been investigated in cows.
M. Arif +5 more
doaj +2 more sources
Nonesterified Fatty Acids, Albumin, and Platelet Aggregation [PDF]
It has been known for five decades that nonesterified fatty acids (NEFAs) have a role in the activation of platelets and thrombosis. Thus, the infusion of NEFAs leads to massive thrombosis and platelet activation (1–4). It has also been shown that their binding to albumin protects the platelets from activation (5).
Sandeep, Dhindsa +2 more
openaire +3 more sources
Association between plasma nonesterified fatty acids species and adipose tissue fatty acid composition. [PDF]
Fatty acid composition of adipose tissue (AT) is an established long-term biomarker for fatty acid (FA) intake and status, but AT samples are not easily available.
Christian Hellmuth +5 more
doaj +2 more sources
Quantitative extraction and determination of nonesterified fatty acids in plasma
A method is described for the determination of nonesterified fatty acids in plasma. Extraction is at least 98% efficient, and losses during subsequent stages are corrected for by the use of an internal radioactive standard.
W.G. Duncombe, T.J. Rising
doaj +3 more sources
Fat Oxidation, But Not Subcutaneous Adipose Tissue Lipolysis, Differs Between Males and Females During a Treadmill‐Based Heat Tolerance Test [PDF]
ABSTRACT This study aimed to determine whether fat metabolism differs between males and females when exposed to extreme exercise‐heat stress. Physically active males (n = 11, 23 ± 4 years, 81.7 ± 11.8 kg, body fat 16.4 ± 6.6%) and females (n = 13, 25 ± 4 years, 60.4 ± 7.1 kg, 24.4 ± 6.7%) completed a 2‐h exercise‐heat tolerance test (40° $\boldsymbol{{}
Margaret C. Morrissey‐Basler +6 more
wiley +2 more sources
G Protein‐Coupled Receptor 17 (Gpr17) Enhances Leptin and Insulin Sensitivity in Lean and Obese Mouse Models [PDF]
This study identifies G protein‐coupled receptor 17 (Gpr17) as a novel regulator of leptin and insulin sensitivity. Using complementary knockout models, we demonstrate that Gpr17 deletion enhances energy expenditure, restores leptin responsiveness, and improves insulin sensitivity, revealing Gpr17 as a potential therapeutic GPCR target for obesity and ...
Xun Sun +8 more
wiley +2 more sources
Circulating concentrations of nonesterified fatty acids (NEFAs) are elevated due to lipid mobilization from adipose tissue in periparturient dairy cows.
Siqing Mao +12 more
doaj +2 more sources
Chia Oil Supplementation Attenuates Obesity‐Induced Hepatic Steatosis, PVAT Inflammation, and Endothelial Dysfunction in Mice [PDF]
We studied whether chia oil, rich in healthy omega‐3 fats, could improve health in obese mice. The oil reduced fat accumulation in the liver, decreased inflammation around blood vessels, and helped blood vessels relax better. These results suggest chia oil may help prevent complications of obesity, like fatty liver and heart disease.
Agatha de Assis‐Ferreira +10 more
wiley +2 more sources

